Journal
ADVANCED MATERIALS
Volume 22, Issue 24, Pages 2672-+Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201000151
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Funding
- National Natural Science Foundation [20725516, 90913014]
- Ministry of Science and Technology [2007CB936000, 2006AA02A407, 2006CB910601, 2006BAI05A05, 2007CB947300, 07DZ22917]
- Ministry of Health [2009ZX10004-301]
- Shanghai Leading Academic Discipline Project [B205]
- Shanghai Municipality Science & Technology Commission [05JC14090, 0952nm04600]
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A solution-phase DNA chip is produced using DNA origami-based asymmetric self-assembled tiles incorporating single-stranded DNA linear probes. This DNA origami chip is fully spatially addressable, without having to use position index oligonucleotides. The DNA hybridization is readily detected via atomic force microscopy.
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