Journal
ADVANCED MATERIALS
Volume 22, Issue 22, Pages 2454-+Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.200903870
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Funding
- University of Rochester's Clinical and Translational Science Institute [UL1 RR024160]
- National Center for Research Resources (NCRR)
- National Institutes of Health (NIH)
- NIH Roadmap for Medical Research
- [AR051469]
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Aligned straight and wavy fibers of biodegradable poly(D,L-lactic-co-glycolic acid) (PLGA) are fabricated using a magnetic-field-assisted electrospinning method. PLGA fibrous matrices prepared by this method can guide the growth of pluripotent murine mesenchymal stem cells. While the stem cells on the randomly oriented fibers adapt pseudo-sphere-like shape, those on aligned fibers exhibit elongated morphology along the long axes (see figure).
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