4.8 Article

Bionanocomposites as New Carriers for Influenza Vaccines

Journal

ADVANCED MATERIALS
Volume 21, Issue 41, Pages 4167-+

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.200900181

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Funding

  1. CICYT [MAT2006-03356, MAT2008-01937-E, AGL07-60274]
  2. Comunidad de Madrid [S-0505/MAT/000227]
  3. CSIC [PIFCOO_08_00032]

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Bionanocomposites resulting from the assembly of negatively charged polysaccharides (xanthan gum) and sepiolite at the nanometer scale are able to associate efficiently to influenza-virus particles. This produces stable dispersions suitable as effective intranasal or intramuscular flu vaccines, as confirmed from experiments carried out in mice.

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