Synthesis of Core/Shell Colloidal Magnetic Zeolite Microspheres for the Immobilization of Trypsin

Magnetic zeolite microspheres are synthesized by combining sol-gel synthesis and vapor-phase transport. The microspheres, which have magnetite cores and crystalline zeolite shells (see figure), exhibit super-paramagnetism and a high adsorption capacity for trypsin. Trypsin-adsorbed microspheres digest proteins very efficiently (in only 15 s) in the presence of microwave radiation.