4.8 Article

Ultrabubble: A Laminated Ultrasound Contrast Agent with Narrow Size Range

Journal

ADVANCED MATERIALS
Volume 21, Issue 38-39, Pages 3949-+

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.200901096

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A laminated shell microcapsule is described resisting aggregation and withstanding ultrasound destruction, showing a good backscatter signal, as shown in the figure. Templated synthesis produces versatile monodisperse capsules <3 mu m, with ultrasound-pressure dependency allowing rupture above MI similar to 1.5 (at 2 MHz), suitable for future development as both controlled-delivery agent and contrast agent.

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