4.8 Article

Fluorescent Polystyrene-Fe3O4 Composite Nanospheres for In Vivo Imaging and Hyperthermia

Journal

ADVANCED MATERIALS
Volume 21, Issue 21, Pages 2170-+

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.200803159

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Funding

  1. NSF NIRT [EAR-0403732]

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Quantum dots (QDs) are immobilized on the surfaces of magnetic Fe3O4-composite nanospheres (MNSs, see figure). The QDs exhibit intense visible-light emission in fluorescence spectroscopy and successfully facilitate, for the first time, in vivo soft-tissue imaging in live mice. The Fe3O4 nanoparticles respond to an external magnetic field by increasing the temperature of the surrounding environment (i.e., hyperthermia), which can be used therapeutically.

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