Bone-like Resorbable Silk-based Scaffolds for Load-bearing Osteoregenerative Applications

Hydroxyapatite/silk biocompatible composites with unprecedented mechanical strength and toughness areproduced in a new process with theintegrated mineralization of macroporous silk fibroin scaffolds. Thebiomimetic bone-like composites areabsorbable and load-bearing with compressive strength, modulus, andtoughness comparable to the mechanical tolerances of cancellous bone.