4.8 Article

Enhancing the Toxicity of Cancer Chemotherapeutics with Gold Nanorod Hyperthermia

Journal

ADVANCED MATERIALS
Volume 20, Issue 20, Pages 3832-+

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.200800921

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Funding

  1. CIHR
  2. NSERC
  3. CFI
  4. OIT
  5. CFUW
  6. K. M. Hunter Foundation

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The heat produced by optically excited gold nanorods is used to augment the chemotherapeutic agent cisplatin in killing tumor cells. This combined therapy kills 78% more cells than cisplatin alone, suggesting a synergistic interaction between these treatments.

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