Journal
ADVANCED MATERIALS
Volume 20, Issue 18, Pages 3562-+Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.200800936
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Funding
- Office of Naval Research [N000140710801]
- Huck Institute Life Sciences at Penn State
- Pennsylvania State University [DMR 0080019]
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The development of a SERS substrate with high uniformity and sample-to-sample reproducibility is reported. Nanostructured poly(p-xylylene) films are prepared using an oblique-angle polymerization method, and SERS-active metals are deposited onto the nanostructured polymer by using thermal evaporation (see figure). The use of the substrate for a robust and reagentless detection of both Gram-positive and Gram-negative bacteria is demonstrated.
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