Journal
ADVANCED MATERIALS
Volume 20, Issue 11, Pages 2037-+Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.200702088
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A combinatorial method for screening cell-biomaterial interactions in 3D is presented; polymeric, salt-leached scaffolds with varied composition and properties are present in a 96-well plate. Previous high-throughput approaches for screening cell-material interactions have focused on planar 2D surfaces or films. However, biomaterials are commonly used in a 3D scaffold format and cells behave more physiologically when cultured in 3D.
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