Journal
ADVANCED MATERIALS
Volume 20, Issue 4, Pages 706-+Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.200702224
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By using AuNP-modified homo-adenine DNA conjugate as a model system, simple colorimetric and resonance Rayleigh scattering assays have been developed for screening small molecules that trigger the formation of the non-Watson-Crick homo-adenine duplexes. The assay presented here is more simplified in format as it involves only one type of ssDNA modified Au-NP, and can be easily adapted to high-throughput screening.
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