Journal
ADVANCED FUNCTIONAL MATERIALS
Volume 24, Issue 38, Pages 5936-5955Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adfm.201401664
Keywords
nanobiology; nanoparticles; nanomaterials; nanomedicine; nanotechnology; biomedicine
Categories
Funding
- Ministry of Education, Singapore [R-279-000-350-112, R-279-000-376-112]
- HSFP [RGP0052/2012]
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In nanomedicine design, emphasis is centered on the engineered impacts of the nanomaterials (NMs). However, failure to understand the unintended effects of nanomaterials on the cell biology can affect the overall performance, approval, and adoption in the clinic. Much of these unintended effects arise from unique physico-chemical properties of the NMs. This feature article discusses some of the key physico-chemical parameters of NMs and highlights how they could cause unexpected and novel biological responses, with some insights into their underlying mechanisms.
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