4.8 Review

New Generation of Multifunctional Nanoparticles for Cancer Imaging and Therapy

Journal

ADVANCED FUNCTIONAL MATERIALS
Volume 19, Issue 10, Pages 1553-1566

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adfm.200801655

Keywords

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Funding

  1. Real-Time Molecular Imaging Project
  2. GIRL Project of MEST
  3. Intramural Research Program of the KIST
  4. National Research Council of Science & Technology (NST), Republic of Korea [2E21250] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
  5. National Research Foundation of Korea [2006-2003764] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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Advances in nanotechnology have contributed to the development of novel nanoparticles that enable the tumor-specific delivery of imaging probes and therapeutic agents in cancer imaging and therapy. Nanobiotechnology combines nanotechnology with molecular imaging, which has led to the generation of new multifunctional nanoparticles for cancer imaging and therapy. Multifunctional nanoparticles hold great promise for the future of cancer treatment because they can detect the early onset of cancer in each individual patient and deliver suitable therapeutic agents to enhance therapeutic efficacy. The combination of tumor-targeted imaging and therapy in an all-in-one system provides a useful multimodal approach in the battle against cancer. Novel multifunctional nanoparticles thus offer a new avenue in the application of personalized medicine in the near future. Herein, new trends and the significance of novel multifunctional nanoparticles in cancer imaging and therapy are reviewed.

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