Journal
ADVANCED DRUG DELIVERY REVIEWS
Volume 63, Issue 6, Pages 456-469Publisher
ELSEVIER
DOI: 10.1016/j.addr.2011.02.001
Keywords
Drug nanoparticles; Nanosuspensions; Physical stability; Chemical stability; Stabilizer
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As nano-sizing is becoming a more common approach for pharmaceutical product development, researchers are taking advantage of the unique inherent properties of nanoparticles for a wide variety of applications. This article reviews the physical and chemical stability of drug nanoparticles, including their mechanisms and corresponding characterization techniques. A few common strategies to overcome stability issues are also discussed. Published by Elsevier B.V.
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