Journal
ACTA TROPICA
Volume 119, Issue 1, Pages 1-4Publisher
ELSEVIER
DOI: 10.1016/j.actatropica.2011.04.002
Keywords
Trypanosoma cruzi I; DTUs; Genetic variability; Mini-exon; Microsatellites
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Trypanosoma cruzi the aethiological agent of Chagas disease, a complex zoonoses that affects the American continent is a genetically variable parasite subdivided into six Discrete Typing Units (DTUs). T. cruzi I is the most prevalent DTU affecting the northern countries of America with sporadical cases in the southern countries. T. cruzi I has shown great genetic diversity showing plausible subdivisions needed for this group. Recently. Tcl has gained novel importance because of the lately discovered relation with cardiomyopathy manifestations that raises the importance of establishing subdivisions within this DTU. (C) 2011 Elsevier BM. All rights reserved.
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