Journal
ACTA TROPICA
Volume 114, Issue 3, Pages 131-137Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.actatropica.2009.10.025
Keywords
Erythrocyte; Invasion; Plasmodium; EBL; RBL; DARC
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The intracellular trafficking of an Erythrocyte Binding Like (EBL) ligand has recently been shown to dramatically affect the multiplication rate and virulence of the rodent malaria parasite Plasmodium yoelii yoelii. In this review, we describe the current understanding of the role of EBL and other erythrocyte binding ligands in erythrocyte invasion, and discuss the mechanisms by which they may control multiplication rates and virulence in malaria parasites. (C) 2009 Elsevier B.V. All rights reserved.
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