Journal
JOURNAL OF BEHAVIOR THERAPY AND EXPERIMENTAL PSYCHIATRY
Volume 41, Issue 2, Pages 145-149Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.jbtep.2009.11.007
Keywords
Bipolar disorder; Sleep; Mood; Delayed phase; Sleep efficiency
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Funding
- NIMH NIH HHS [R34 MH080958, R34 MH080958-01A2] Funding Source: Medline
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We investigated associations between sleep, illness course, and concurrent symptoms in 21 participants with bipolar disorder who were inter-episode. Sleep was assessed using a week-long diary. Illness course and symptoms were assessed via validated semi-structured interviews. Lower and more variable sleep efficiency and more variable total wake time were associated with more lifetime depressive episodes. Variability in failing asleep time was positively correlated with concurrent depressive symptoms. Sleep efficiency was positively correlated with concurrent manic symptoms. These findings suggest that inter-episode sleep disturbance is associated with illness course and that sleep may be an important intervention target in bipolar disorder. (c) 2009 Elsevier Ltd. All rights reserved.
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