Journal
ACTA PHYSIOLOGICA
Volume 213, Issue 2, Pages 384-393Publisher
WILEY
DOI: 10.1111/apha.12406
Keywords
arrhythmia; gastroparesis; interstitial cells of Cajal; slow wave patterns; smooth muscle
Categories
Funding
- Health Research Council of New Zealand
- NIH [DK674775]
- Fraunhofer-Bessel Research Award from the Alexander von Humboldt Foundation
- Fraunhofer-Gesellschaft
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This review provides an overview of our understanding of motility and slow wave propagation in the stomach. It begins by reviewing seminal studies conducted by Walter Cannon and Augustus Waller on in vivo motility and slow wave patterns. Then our current understanding of slow wave patterns in common laboratory animals and humans is presented. The implications of slow wave arrhythmic patterns that have been recorded in animals and patients suffering from gastroparesis are discussed. Finally, current challenges in experimental methods and techniques, slow wave modulation and the use of mathematical models are discussed.
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