Journal
ACTA PHYSIOLOGICA
Volume 198, Issue 4, Pages 417-430Publisher
WILEY
DOI: 10.1111/j.1748-1716.2009.02073.x
Keywords
macrocirculation; microcirculation; pulse wave reflection
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Physiologically, macro- and microcirculation differ markedly as macrocirculation deals with pulsatile pressure and flow and microcirculation with steady pressure and flow. Various such haemodynamic aspects correspond to a large heterogeneity in the structure and function of the vascular tree. In the past, diseases such as hypertension and diabetes mellitus were classified on the basis of the structure and function of small and large arteries. The purpose of this paper is to review the cross-talk between the micro- and macrocirculation. We shall discuss this cross-talk from the perspective of the development, physiology and pathology of the entire arterial tree.
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