Journal
ACTA PHYSIOLOGICA
Volume 198, Issue 3, Pages 263-275Publisher
WILEY
DOI: 10.1111/j.1748-1716.2009.02015.x
Keywords
acetylcholine; dopamine; histamine; hypocretin; noradrenaline; serotonin
Categories
Ask authors/readers for more resources
Orexin/hypocretin neurones in the posterior hypothalamus are mutually connected with noradrenergic, serotonergic, dopaminergic, histaminergic, and cholinergic neurone systems. They activate these targets by direct post-synaptic and indirect pre-synaptic mechanisms and in turn receive inhibitory feedback and excitatory feed forward control. With respect to behavioural state control, orexin/hypocretin neurones are conducting the orchestra of biogenic amines. This review highlights the role of these players in the control of energy administration, sleep-wake architecture, cortical activation, plasticity, and memory functions in health and disease.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available