Related references
Note: Only part of the references are listed.Rapamycin Causes Upregulation of Autophagy and Impairs Islets Function Both In Vitro and In Vivo
M. Tanemura et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2012)
Raman microspectroscopy of live cells under autophagy-inducing conditions
Stanislav O. Konorov et al.
ANALYST (2012)
The regulatory mechanism of 4-phenylbutyric acid against ER stress-induced autophagy in human gingival fibroblasts
Do-Sung Kim et al.
ARCHIVES OF PHARMACAL RESEARCH (2012)
Loss of the starvation-induced gene Rack1 leads to glycogen deficiency and impaired autophagic responses in Drosophila
Balazs Erdi et al.
AUTOPHAGY (2012)
The role of autophagy in endoplasmic reticulum stress-induced pancreatic β cell death
Jia-Jing Yin et al.
AUTOPHAGY (2012)
Lys05 A new lysosomal autophagy inhibitor
Ravi K. Amaravadi et al.
AUTOPHAGY (2012)
Autophagy is a protective response to ethanol neurotoxicity
Gang Chen et al.
AUTOPHAGY (2012)
A novel image-based cytometry method for autophagy detection in living cells
Leo Li-Ying Chan et al.
AUTOPHAGY (2012)
GDC-0941, a Novel Class I Selective PI3K Inhibitor, Enhances the Efficacy of Docetaxel in Human Breast Cancer Models by Increasing Cell Death In Vitro and In Vivo
Jeffrey J. Wallin et al.
CLINICAL CANCER RESEARCH (2012)
Identification of Autophagosome-associated Proteins and Regulators by Quantitative Proteomic Analysis and Genetic Screens
Joern Dengjel et al.
MOLECULAR & CELLULAR PROTEOMICS (2012)
Targeting microRNA-30a-mediated autophagy enhances imatinib activity against human chronic myeloid leukemia cells
Y. Yu et al.
LEUKEMIA (2012)
Autophagic degradation of tau in primary neurons and its enhancement by trehalose
Ulrike Krueger et al.
NEUROBIOLOGY OF AGING (2012)
Long-term oral lithium treatment attenuates motor disturbance in tauopathy model mice: Implications of autophagy promotion
Kohei Shimada et al.
NEUROBIOLOGY OF DISEASE (2012)
p53 MEDIATES AUTOPHAGY ACTIVATION AND MITOCHONDRIA DYSFUNCTION IN KAINIC ACID-INDUCED EXCITOTOXICITY IN PRIMARY STRIATAL NEURONS
X. X. Dong et al.
NEUROSCIENCE (2012)
Inhibitors of Phosphatidylinositol 3′-Kinases Promote Mitotic Cell Death in HeLa Cells
Heli Hou et al.
PLOS ONE (2012)
Autophagy Suppresses RIP Kinase-Dependent Necrosis Enabling Survival to mTOR Inhibition
Kevin Bray et al.
PLOS ONE (2012)
Chloroquine-Mediated Lysosomal Dysfunction Enhances the Anticancer Effect of Nutrient Deprivation
Ljubica Harhaji-Trajkovic et al.
PHARMACEUTICAL RESEARCH (2012)
Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency
Quentin McAfee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment
Alberto M. Martelli et al.
ONCOTARGET (2012)
Temsirolimus in the treatment of relapsed and/or refractory mantle cell lymphoma
Sara Galimberti
Cancer Management and Research (2012)
Resveratrol in cardiovascular health and disease
Goran Petrovski et al.
RESVERATROL AND HEALTH (2011)
The Role of Atg Proteins in Autophagosome Formation
Noboru Mizushima et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27 (2011)
Cardioprotection by Endoplasmic Reticulum Stress-Induced Autophagy
Goran Petrovski et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
Ins(1,4,5)P3 receptor-mediated Ca2+ signaling and autophagy induction are interrelated
Jean-Paul Decuypere et al.
AUTOPHAGY (2011)
Beclin 1-independent autophagy contributes to apoptosis in cortical neurons
Yulia Grishchuk et al.
AUTOPHAGY (2011)
Dissecting the dynamic turnover of GFP-LC3 in the autolysosome
Hong-Min Ni et al.
AUTOPHAGY (2011)
Discovery and biological activity of a novel class I PI3K inhibitor, CH5132799
Jun Ohwada et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)
Beclin1 Controls the Levels of p53 by Regulating the Deubiquitination Activity of USP10 and USP13
Junli Liu et al.
CELL (2011)
microRNA-101 is a potent inhibitor of autophagy
Lisa B. Frankel et al.
EMBO JOURNAL (2011)
A small-molecule enhancer of autophagy decreases levels of Aβ and APP-CTF via Atg5-dependent autophagy pathway
Yuan Tian et al.
FASEB JOURNAL (2011)
Oridonin: An active diterpenoid targeting cell cycle arrest, apoptotic and autophagic pathways for cancer therapeutics
Chun-yang Li et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2011)
Autophagosomes and human diseases
Isabelle Beau et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2011)
The autophagy-inducing drug carbamazepine is a radiation protector and mitigator
Hyun Kim et al.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2011)
HDAC6 regulates aggresome-autophagy degradation pathway of α-synuclein in response to MPP plus -induced stress
Min Su et al.
JOURNAL OF NEUROCHEMISTRY (2011)
GDC-0980 Is a Novel Class I PI3K/mTOR Kinase Inhibitor with Robust Activity in Cancer Models Driven by the PI3K Pathway
Jeffrey J. Wallin et al.
MOLECULAR CANCER THERAPEUTICS (2011)
DEPTOR, an mTOR Inhibitor, Is a Physiological Substrate of SCFβTrCP E3 Ubiquitin Ligase and Regulates Survival and Autophagy
Yongchao Zhao et al.
MOLECULAR CELL (2011)
Distinct Autophagosomal-Lysosomal Fusion Mechanism Revealed by Thapsigargin-Induced Autophagy Arrest
Ian G. Ganley et al.
MOLECULAR CELL (2011)
POTENTIAL AUTOPHAGY ENHANCERS ATTENUATE ROTENONE-INDUCED TOXICITY IN SH-SY5Y
N. Xiong et al.
NEUROSCIENCE (2011)
A Mechanism for Synergy with Combined mTOR and PI3 Kinase Inhibitors
Shujie Yang et al.
PLOS ONE (2011)
Quality control autophagy A joint effort of ubiquitin, protein deacetylase and actin cytoskeleton
Joo-Yong Lee et al.
AUTOPHAGY (2010)
ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy
Liang Qin et al.
AUTOPHAGY (2010)
Calpains and proteasomes mediate degradation of ryanodine receptors in a model of cardiac ischemic reperfusion
Zully Pedrozo et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)
p38 Mitogen-Activated Protein Kinase is Involved in Endoplasmic Reticulum Stress-Induced Cell Death and Autophagy in Human Gingival Fibroblasts
Do-Sung Kim et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2010)
Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3
Fiona M. Menzies et al.
BRAIN (2010)
p62 (SQSTM1) and cyclic AMP phosphodiesterase-4A4 (PDE4A4) locate to a novel, reversible protein aggregate with links to autophagy and proteasome degradation pathways
Frank Christian et al.
CELLULAR SIGNALLING (2010)
HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy
Joo-Yong Lee et al.
EMBO JOURNAL (2010)
Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase
You-Tong Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Phosphorylated α-Synuclein at Ser-129 Is Targeted to the Proteasome Pathway in a Ubiquitin-independent Manner
Youhei Machiya et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Paeoniflorin, a potent natural compound, protects PC12 cells from MPP+ and acidic damage via autophagic pathway
Bi-Yin Cao et al.
JOURNAL OF ETHNOPHARMACOLOGY (2010)
Autophagy Induction with RAD001 Enhances Chemosensitivity and Radiosensitivity through Met Inhibition in Papillary Thyroid Cancer
Chi-Iou Lin et al.
MOLECULAR CANCER RESEARCH (2010)
Autophagy induced by valproic acid is associated with oxidative stress in glioma cell lines
Jun Fu et al.
NEURO-ONCOLOGY (2010)
Shaping Development of Autophagy Inhibitors with the Structure of the Lipid Kinase Vps34
Simon Miller et al.
SCIENCE (2010)
An Autophagy-Enhancing Drug Promotes Degradation of Mutant α1-Antitrypsin Z and Reduces Hepatic Fibrosis
Tunda Hidvegi et al.
SCIENCE (2010)
Inhibition of PI3k Class III-Dependent Autophagy Prevents Apoptosis and Necrosis by Oxidative Stress in Dopaminergic Neuroblastoma Cells
Roberta Castino et al.
TOXICOLOGICAL SCIENCES (2010)
Autophagosome Formation Depends on the Small GTPase Rab1 and Functional ER Exit Sites
Felipe Carlos Martin Zoppino et al.
TRAFFIC (2010)
RAD001 (everolimus) induces autophagy in acute lymphoblastic leukemia
Roman Crazzolara et al.
AUTOPHAGY (2009)
Autophagy induction by trehalose counteracts cellular prion infection
Yasmine Aguib et al.
AUTOPHAGY (2009)
Inhibition of macroautophagy by bafilomycin A1 lowers proliferation and induces apoptosis in colon cancer cells
Ya Chun Wu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies
S. Sarkar et al.
CELL DEATH AND DIFFERENTIATION (2009)
The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1
J. M. Vicencio et al.
CELL DEATH AND DIFFERENTIATION (2009)
Autophagy: Regulation and role in disease
Alfred J. Meijer et al.
CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES (2009)
Autophagy-A double-edged sword in oncology
Anja Apel et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1
Carson C. Thoreen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Hydroxychloroquine Modulates Metabolic Activity and Proliferation and Induces Autophagic Cell Death of Human Dermal Fibroblasts
Bettina Ramser et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2009)
Hydroxychloroquine Induces Autophagic Cell Death of Human Dermal Fibroblasts: Implications for Treating Fibrotic Skin Diseases
Aarne Oikarinen
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2009)
Discovery of Atg5/Atg7-independent alternative macroautophagy
Yuya Nishida et al.
NATURE (2009)
Endoplasmic reticulum stress induces autophagy in renal proximal tubular cells
Takahisa Kawakami et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2009)
MPP+ impairs autophagic clearance of alpha-synuclein by impairing the activity of dynein
Zeng-Lin Cai et al.
NEUROREPORT (2009)
Class I phosphatidylinositol 3-kinase inhibitor LY294002 activates autophagy and induces apoptosis through p53 pathway in gastric cancer cell line SGC7901
Chungen Xing et al.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2008)
Does bafilomycin A(1) block the fusion of autophagosomes with lysosomes?
Daniel J. Klionsky et al.
AUTOPHAGY (2008)
Autophagy in the pathogenesis of disease
Beth Levine et al.
CELL (2008)
A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin
Sovan Sarkar et al.
HUMAN MOLECULAR GENETICS (2008)
Small molecule regulators of autophagy identified by an image-based high-throughput screen
Lihong Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Small molecule enhancers of rapamycin-induced TOR inhibition promote autophagy, reduce toxicity in Huntington's disease models and enhance killing of mycobacteria by macrophages
R. Andres Floto et al.
AUTOPHAGY (2007)
Rapamycin: Something old, something new, sometimes borrowed and now renewed
C. M. Hartford et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2007)
The inositol trisphosphate receptor in the control of autophagy
Alfredo Criollo et al.
AUTOPHAGY (2007)
Small molecules enhance autophagy and reduce toxicity in Huntington's disease models
Sovan Sarkar et al.
NATURE CHEMICAL BIOLOGY (2007)
Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and α-synuclein
Sovan Sarkar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival
Wen-Xing Ding et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells
Carolyn Cao et al.
CANCER RESEARCH (2006)
Autophagic stress in neuronal injury and disease
Charleen T. Chu
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2006)
Rapamycin pre-treatment protects against apoptosis
B Ravikumar et al.
HUMAN MOLECULAR GENETICS (2006)
TOR signaling in growth and metabolism
S Wullschleger et al.
CELL (2006)
Functional specificity of the mammalian Beclin-Vps34 Pl 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking
XH Zeng et al.
JOURNAL OF CELL SCIENCE (2006)
TOR signaling in growth and metabolism
Stephan Wullschleger et al.
CELL (2006)
Molecular mechanism and regulation of autophagy
YP Yang et al.
ACTA PHARMACOLOGICA SINICA (2005)
Growing roles for the mTOR pathway
DD Sarbassov et al.
CURRENT OPINION IN CELL BIOLOGY (2005)
Lithium induces autophagy by inhibiting inositol monophosphatase
S Sarkar et al.
JOURNAL OF CELL BIOLOGY (2005)
Amino acid deprivation induces both apoptosis and autophagy in murine C2C12 muscle cells
W Martinet et al.
BIOTECHNOLOGY LETTERS (2005)
Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy
Isei Tanida et al.
AUTOPHAGY (2005)
MTOR-targeted therapy of cancer with rapamycin derivatives
S Vignot et al.
ANNALS OF ONCOLOGY (2005)
Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1
F Scarlatti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
3-methyladenine inhibits autophagy in tobacco culture cells under sucrose starvation conditions
C Takatsuka et al.
PLANT AND CELL PHYSIOLOGY (2004)
Autophagy in health and disease: A double-edged sword
T Shintani et al.
SCIENCE (2004)
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
B Ravikumar et al.
NATURE GENETICS (2004)
The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress
Y Kawaguchi et al.
CELL (2003)
A unified nomenclature for yeast autophagy-related genes
DJ Klionsky et al.
DEVELOPMENTAL CELL (2003)
MTOR interacts with Raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
DH Kim et al.
CELL (2002)
LY294002, but not wortmannin, increases intracellular calcium and inhibits calcium transients in bovine and human airway smooth muscle cells
MF Ethier et al.
CELL CALCIUM (2002)
The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway
S Arico et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The relationship between lumenal and limiting membranes in swollen late endocytic compartments formed after wortmannin treatment or sucrose accumulation
NA Bright et al.
TRAFFIC (2001)
Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network
A Kihara et al.
EMBO REPORTS (2001)
Molecular dissection of autophagy: Two ubiquitin-like systems
Y Ohsumi
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2001)
Distinct classes of phosphatidylinositol 3′-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells
A Petiot et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Share Paper
