4.7 Review

Poly(ADP-ribose) polymerase inhibitors as promising cancer therapeutics

Related references

Note: Only part of the references are listed.
Review Oncology

Triple-Negative Breast Cancer Role of Specific Chemotherapy Agents

Steven J. Isakoff

CANCER JOURNAL (2010)

Review Oncology

Triple-negative/basal-like breast cancer: clinical, pathologic and molecular features

Ramachandran Venkitaraman

EXPERT REVIEW OF ANTICANCER THERAPY (2010)

Article Biochemistry & Molecular Biology

PARP-3 Is a Mono-ADP-ribosylase That Activates PARP-1 in the Absence of DNA

Olga Loseva et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Chemistry, Medicinal

Evolution of Poly(ADP-ribose) Polymerase-1 (PARP-1) Inhibitors. From Concept to Clinic

Dana V. Ferraris

JOURNAL OF MEDICINAL CHEMISTRY (2010)

Article Oncology

ATM Deficiency Sensitizes Mantle Cell Lymphoma Cells to Poly(ADP-Ribose) Polymerase-1 Inhibitors

Chris T. Williamson et al.

MOLECULAR CANCER THERAPEUTICS (2010)

Review Oncology

PARP inhibition: PARP1 and beyond

Michele Rouleau et al.

NATURE REVIEWS CANCER (2010)

Review Pharmacology & Pharmacy

The Importance of NAD in Multiple Sclerosis

W. Todd Penberthy et al.

CURRENT PHARMACEUTICAL DESIGN (2009)

Article Medicine, Research & Experimental

Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors

Ana M. Mendes-Pereira et al.

EMBO MOLECULAR MEDICINE (2009)

Review Pharmacology & Pharmacy

Development of PARP inhibitors in oncology

Jordi Rodon et al.

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2009)

Review Chemistry, Medicinal

Poly(ADP-ribose) polymerase inhibition in cancer therapy: are we close to maturity?

Gianluca Papeo et al.

EXPERT OPINION ON THERAPEUTIC PATENTS (2009)

Article Chemistry, Medicinal

Structural Basis for Inhibitor Specificity in Human Poly(ADP-ribose) Polymerase-3

Lari Lehtio et al.

JOURNAL OF MEDICINAL CHEMISTRY (2009)

Editorial Material Oncology

PARP Inhibitors: Will the New Class of Drugs Match the Hype?

Rabiya S. Tuma

JOURNAL OF THE NATIONAL CANCER INSTITUTE (2009)

Article Multidisciplinary Sciences

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

Shih-Min A. Huang et al.

NATURE (2009)

Article Biochemistry & Molecular Biology

Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

Baozhi Chen et al.

NATURE CHEMICAL BIOLOGY (2009)

Article Medicine, General & Internal

Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers.

Peter C. Fong et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Article Cell Biology

Wnt/β-catenin signaling:: new (and old) players and new insights

He Huang et al.

CURRENT OPINION IN CELL BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Substrate-Assisted Catalysis by PARP10 Limits Its Activity to Mono-ADP-Ribosylation

Henning Kleine et al.

MOLECULAR CELL (2008)

Article Multidisciplinary Sciences

Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers

Wataru Sakai et al.

NATURE (2008)

Article Multidisciplinary Sciences

Tankyrase 1 and Tankyrase 2 Are Essential but Redundant for Mouse Embryonic Development

Y. Jeffrey Chiang et al.

PLOS ONE (2008)

Article Multidisciplinary Sciences

High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs

Sven Rottenberg et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Review Biochemistry & Molecular Biology

Toward specific functions of poly(ADP-ribose) polymerase-2

Jose Yelamos et al.

TRENDS IN MOLECULAR MEDICINE (2008)

Review Oncology

DNA repair pathways as targets for cancer therapy

Thomas Helleday et al.

NATURE REVIEWS CANCER (2008)

Article Biochemistry & Molecular Biology

The role of the poly(ADP-ribose) polymerase tankyrase1 in telomere length control by the TRF1 component of the shelterin complex

Jill R. Donigian et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

PARP-2 deficiency affects the survival of CD4+CD8+ double-positive thymocytes

Jose Yelamos et al.

EMBO JOURNAL (2006)

Review Cell Biology

Poly(ADP-ribose):: novel functions for an old molecule

Valerie Schreiber et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)

Review Pharmacology & Pharmacy

Emerging cancer therapeutic opportunities target DNA-repair systems

Jian Ding et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2006)

Review Chemistry, Multidisciplinary

Molecular basis of ataxia telangiectasia and related diseases

LG Ball et al.

ACTA PHARMACOLOGICA SINICA (2005)

Article Multidisciplinary Sciences

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

H Farmer et al.

NATURE (2005)

Article Biochemistry & Molecular Biology

Crystal structure of the catalytic fragment of murine poly(ADP-ribose) polymerase-2

AW Oliver et al.

NUCLEIC ACIDS RESEARCH (2004)

Article Biochemistry & Molecular Biology

A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage

SF El-Khamisy et al.

NUCLEIC ACIDS RESEARCH (2003)

Review Biochemistry & Molecular Biology

Centromere proteins Cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and are poly(ADP-ribosyl)ated

A Saxena et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1

V Schreiber et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Role for the related poly(ADP-ribose) polymerases tankyrase 1 and 2 at human telomeres

BD Cook et al.

MOLECULAR AND CELLULAR BIOLOGY (2002)

Article Biochemistry & Molecular Biology

TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression

PG Kaminker et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Biochemistry & Molecular Biology

BRCA1 and BRCA2 and the genetics of breast and ovarian cancer

PL Welcsh et al.

HUMAN MOLECULAR GENETICS (2001)

Review Oncology

BRCA1 and prostate cancer

EM Rosen et al.

CANCER INVESTIGATION (2001)

Article Biochemistry & Molecular Biology

Tankyrase promotes telomere elongation in human cells

S Smith et al.

CURRENT BIOLOGY (2000)