Journal
ACTA PHARMACOLOGICA SINICA
Volume 31, Issue 9, Pages 1071-1074Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/aps.2010.140
Keywords
psychostimulants; oxytocin; cocaine; methamphetamine; dopamine; glutamate
Funding
- Key Laboratory for New Drug Screening and Key Laboratory for Pharmacodynamics of Liaoning Province
- Outstanding Youth Fund of Liaoning province
- National Key Scientific Project for New Drug Discovery and Development, China [2009ZX09301-012]
Ask authors/readers for more resources
Psychostimulants are frequently abused as a result of their stimulatory effects on several neurotransmitter systems within the central nervous system. Both dopaminergic and glutaminergic neurotransmissions have been closely associated with psychostimulant dependence. In addition to its classical endocrine function in the periphery, oxytocin, an important neurohypophyseal neuropeptide in the central nervous system, has a wide range of behavioral effects, including regulating drug abuse. The present paper reviews the progress of research into the role of oxytocin in reducing psychostimulant-induced psychological dependence and the mechanisms by which oxytocin mediates its effects.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available