4.7 Article

Planar Mn4O Cluster Homochiral Metal-Organic Framework for HPLC Separation of Pharmaceutically Important (±)-Ibuprofen Racemate

Journal

INORGANIC CHEMISTRY
Volume 54, Issue 8, Pages 3713-3715

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ic502861k

Keywords

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Funding

  1. NSFC [21365021, 21371147, 21401119]
  2. XJNSF [2013711009, 2013211A026, XJGRI2013132]

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A planar tetracoordinated oxygen containing a homochiral metalorganic framework (MOF) has been synthesized and characterized that can be used as a new chiral stationary phase in high-performance liquid chromatography to efficiently separate racemates such as pharmaceutically important (+/-)-ibuprofen and (+/-)-1-phenyl-1,2-ethanediol.

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