Journal
ACTA PHARMACEUTICA
Volume 60, Issue 3, Pages 339-348Publisher
HRVATSKO FARMACEUTSKO DRUSTOV (HFD)-CROATION PHARMACEUTICAL SOC
DOI: 10.2478/v10007-010-0028-5
Keywords
Plantago psyllium (Plantaginaceae); mucilage; paracetamol; binder; release
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Funding
- Research Council of the Mazandaran University of Medical Sciences
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Mucilage extracted from Planing psyllium seeds was evaluated for inertness and safety parameters. The suitability of psyllium mucilage for a pharmaceutical binder was assessed in paracetamol tablets. Properties of the granules prepared using different concentrations of psyllium mucilage was compared with PVP and tragacanth. Psyllium mucilage at 5 % (m/m) was found to be comparable with 3 % (m/m) of PVP. Investigated paracetamol tablets indicated that psyllium mucilage can retard the drug release.
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