Journal
ACTA OTO-LARYNGOLOGICA
Volume 134, Issue 3, Pages 260-267Publisher
TAYLOR & FRANCIS LTD
DOI: 10.3109/00016489.2013.831478
Keywords
Pterygoid canal; cytokine; vasoactive intestinal polypeptide; calcitonin gene-related peptide; substance P; interleukin-4; interleukin-5; rhinoconjunctivitis quality of life questionnaire
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Conclusion: Our results indicate that vidian neurectomy may be recommended as an effective method for the treatment of vasomotor rhinitis (VMR). Objective: The aim of this work was to study the feasibility and effectiveness of vidian neurectomy treatment under the nasal endoscope for VMR. Methods: The study included 45 patients with VMR. They were all assigned to functional endoscopic surgery with vidian neurectomy. Results: The obtained data showed that, using the rhinoconjunctivitis quality of life questionnaire, vidian neurectomy treatment relieved the symptoms of VMR in 82.2% of the patients. Vidian neurectomy also led to the reduction of expression of several cytokines, including vasoactive intestinal polypeptide, calcitonin gene-related peptide, substance P, interleukin (IL)-4, and IL-5.
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