Journal
ACTA OTO-LARYNGOLOGICA
Volume 132, Issue 3, Pages 241-246Publisher
TAYLOR & FRANCIS LTD
DOI: 10.3109/00016489.2011.639085
Keywords
Endolymphatic hydrops; magnetic resonance imaging; MRI; barotrauma
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Funding
- Ministry of Education, Culture, Sports, Science and Technology [B 21390460]
- Ministry of Health, Labor and Welfare in Japan [H23-Nanchi-Ippan-021]
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Conclusion. Contrast enhancement of the inner ear by three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging (3D-FLAIR MRI) taken 4 h after intravenous gadolinium (Gd) injection was better than when taken at 10 min. Using heavily T2-weighted 3D-FLAIR MRI, visualization of endolymphatic hydrops (EH) was possible in the vestibule and the cochlea after a standard intravenous dose of Gd. Objectives. To define a suitable time point for imaging Gd uptake in the inner ear acquired with heavily T2-weighted 3D-FLAIR MRI after standard intravenous Gd administration. Methods: Using a 3 Tesla MRI unit, heavily T2-weighted 3D-FLAIR MRI images were taken twice at approximately 10 min (conventional timing) and 4 h after intravenous gadodiamide (0.1 mmol/kg) injection in 10 patients with inner ear diseases including Meniere's disease. Results: The 4 h delay increased Gd enhancement of the 3D-FLAIR MRI images of the perilymphatic space in both symptomatic and asymptomatic ears. The increase in Gd enhancement was greater in symptomatic than in asymptomatic ears. Using this heavily T2-weighted 3D-FLAIR technique, EH was observed in both the cochlea and vestibule in images taken 4 h after the intravenous Gd injection.
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