Related references
Note: Only part of the references are listed.Clearance of dying ARPE-19 cells by professional and nonprofessional phagocytes in vitro - implications for age-related macular degeneration (AMD)
Goran Petrovski et al.
ACTA OPHTHALMOLOGICA (2011)
Autophagy Shapes Inflammation
Laszlo Fesues et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
Influence of Hsp90 and HDAC Inhibition and Tubulin Acetylation on Perinuclear Protein Aggregation in Human Retinal Pigment Epithelial Cells
Tuomas Ryhanen et al.
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2011)
Metabolic physiology in age related macular degeneration
Einar Stefansson et al.
PROGRESS IN RETINAL AND EYE RESEARCH (2011)
Autophagy - hot topic in AMD
Kai Kaarniranta
ACTA OPHTHALMOLOGICA (2010)
Identification of tubby and tubby-like protein 1 as eat-me signals by phage display
Nora B. Caberoy et al.
EXPERIMENTAL CELL RESEARCH (2010)
Effects of lipid peroxidation products on lipofuscinogenesis and autophagy in human retinal pigment epithelial cells
Tim U. Krohne et al.
EXPERIMENTAL EYE RESEARCH (2010)
Dendritic cell physiology and function in the eye
John V. Forrester et al.
IMMUNOLOGICAL REVIEWS (2010)
Endoplasmic Reticulum Stress in Age-Related Macular Degeneration: Trigger for Neovascularization
Antero Salminen et al.
MOLECULAR MEDICINE (2010)
Immune Activation in Retinal Aging: A Gene Expression Study
Mei Chen et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2010)
Heat shock proteins as gatekeepers of proteolytic pathways-Implications for age-related macular degeneration (AMD)
Kai Kaarniranta et al.
AGEING RESEARCH REVIEWS (2009)
Regulatory role of HIF-1 alpha in the pathogenesis of age-related macular degeneration (AMD)
Olli Arjamaa et al.
AGEING RESEARCH REVIEWS (2009)
Autophagy, exosomes and drusen formation in age-related macular degeneration
Ai Ling Wang et al.
AUTOPHAGY (2009)
Autophagy: A lysosomal degradation pathway with a central role in health and disease
Eeva-Liisa Eskelinen et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)
Autophagy Suppresses Tumorigenesis through Elimination of p62
Robin Mathew et al.
CELL (2009)
The retinal oxysterol pathway: a unifying hypothesis for the cause of age-related macular degeneration
Norman B. Javitt et al.
CURRENT OPINION IN OPHTHALMOLOGY (2009)
Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagy-mediated proteolysis in human retinal pigment epithelial cells
Tuomas Ryhanen et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2009)
Characterization of PEDF: A Multi-Functional Serpin Family Protein
S. Filleur et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2009)
Age-related macular degeneration: activation of innate immunity system via pattern recognition receptors
K. Kaarniranta et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2009)
A Role for Ubiquitin in Selective Autophagy
Vladimir Kirkin et al.
MOLECULAR CELL (2009)
Regulation of the aging process by autophagy
Antero Salminen et al.
TRENDS IN MOLECULAR MEDICINE (2009)
Regulation of macroautophagy by mTOR and Beclin 1 complexes
Sophie Pattingre et al.
BIOCHIMIE (2008)
ATF4-dependent transcription is a key mechanism in VEGF up-regulation by oxidized phospholipids:: critical role of oxidized sn-2 residues in activation of unfolded protein response
Olga V. Oskolkova et al.
BLOOD (2008)
Autophagy in the pathogenesis of disease
Beth Levine et al.
CELL (2008)
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
Annett Halle et al.
NATURE IMMUNOLOGY (2008)
Medical progress: Age-related macular degeneration
Rama D. Jager et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Endogenous VEGF Is Required for Visual Function: Evidence for a Survival Role on Muller Cells and Photoreceptors
Magali Saint-Geniez et al.
PLOS ONE (2008)
Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes
Peter Kijun Kim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Mitochondrial proteomics of the retinal pigment epithelium at progressive stages of age-related macular degeneration
Curtis L. Nordgaard et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2008)
The inflammasome:: a danger sensing complex triggering innate immunity
Virginie Petrilli et al.
CURRENT OPINION IN IMMUNOLOGY (2007)
Progress in defining the molecular biology of age related macular degeneration
Andrew Lotery et al.
HUMAN GENETICS (2007)
HTRA1 variant increases risk to neovascular age-related macular degeneration in Chinese population
Fang Lu et al.
VISION RESEARCH (2007)
Pro-inflammatory cytokines increase reactive oxygen species through mitochondria and NADPH oxidase in cultured RPE cells
Dongli Yang et al.
EXPERIMENTAL EYE RESEARCH (2007)
Autophagosome formation: Core machinery and adaptations
Zhiping Xie et al.
NATURE CELL BIOLOGY (2007)
Eicosapentaenoic acid is anti-inflammatory in preventing choroidal neovascularization in mice
Takashi Koto et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2007)
Essential role for MFG-E8 as ligand for αvβ5 integrin in diurnal retinal phagocytosis
Emeline F. Nandrot et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Innate and adaptive immunity through autophagy
Dorothee Schmid et al.
IMMUNITY (2007)
The effect of 17β-estradiol on IL-6 secretion and NF-κB DNA-binding activity in human retinal pigment epithelial cells
Tuomas Paimela et al.
IMMUNOLOGY LETTERS (2007)
Association of the HTRA1 gene variant with age-related macular degeneration in the Japanese population
Keisuke Mori et al.
JOURNAL OF HUMAN GENETICS (2007)
Interleukin-6 receptor-mediated activation of signal transducer and activator of transcription-3 (STAT3) promotes choroidal neovascularization
Kanako Izumi-Nagai et al.
AMERICAN JOURNAL OF PATHOLOGY (2007)
Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells
Heather M. Seitz et al.
JOURNAL OF IMMUNOLOGY (2007)
Identification of novel dendritic cell populations in normal mouse retina
Heping Xu et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2007)
Changes in select redox proteins of the retinal pigment epithelium in age-related macular degeneration
Alejandra Decanini et al.
AMERICAN JOURNAL OF OPHTHALMOLOGY (2007)
The LOC387715 polymorphism and age-related macular degeneration:: Replication in three case-control samples
Robert J. Ross et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2007)
Progression of geographic atrophy and impact of fundus autofluorescence patterns in age-related macular degeneration
Frank G. Holz et al.
AMERICAN JOURNAL OF OPHTHALMOLOGY (2007)
A polymorphism of LOC387715 gene is associated with age-related macular degeneration in the Japanese population
Seiji Tanimoto et al.
NEUROSCIENCE LETTERS (2007)
Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors
Kensuke Miyake
SEMINARS IN IMMUNOLOGY (2007)
Sequestosome 1/p62 - More than just a scaffold
M. Lamar Seibenhener et al.
FEBS LETTERS (2007)
DAMPs, PAMPs and alarmins: all we need to know about danger
Marco E. Bianchi
JOURNAL OF LEUKOCYTE BIOLOGY (2007)
Distinct functions between toll-like receptors 3 and 9 in retinal pigment epithelial cells
Nobuyuki Ebihara et al.
OPHTHALMIC RESEARCH (2007)
A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration
Zhenglin Yang et al.
SCIENCE (2006)
HTRA1 promoter polymorphism in wet age-related macular degeneration
Andrew DeWan et al.
SCIENCE (2006)
The regulation of vascular endothelial growth factors (VEGF-A -C, and -D) expression in the retinal pigment epithelium
Yasuhiro Ikeda et al.
EXPERIMENTAL EYE RESEARCH (2006)
Endoplasmic reticulum stress triggers autophagy
Tomohiro Yorimitsu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Association of the Y402H polymorphism in complement factor H gene and neovascular age-related macular degeneration in Chinese patients
Ling-Ing Lau et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2006)
VEGF expression and receptor activation in the choroid during development and in the adult
Magali Saint-Geniez et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2006)
The expression of advanced glycation endproduct receptors in rpe cells associated with basal deposits in human maculas
Yuko Yamada et al.
EXPERIMENTAL EYE RESEARCH (2006)
Inflammation and the apopto-phagocytic system
G Májai et al.
IMMUNOLOGY LETTERS (2006)
p62/SQSTM1 - A missing link between protein aggregates and the autophagy machinery
Geir Bjorkoy et al.
AUTOPHAGY (2006)
Apolipoprotein (APOE) gene is associated with progression of age-related macular degeneration (AMD)
PN Baird et al.
HUMAN MUTATION (2006)
TLR4 mediates human retinal pigment epithelial endotoxin binding and cytokine expression
SG Elner et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
Autophagy: molecular machinery for self-eating
T Yorimitsu et al.
CELL DEATH AND DIFFERENTIATION (2005)
Understanding RAGE, the receptor for advanced glycation end products
A Bierhaus et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2005)
Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk
A Rivera et al.
HUMAN MOLECULAR GENETICS (2005)
Bruch's membrane and the vascular intima: is there a common basis for age-related changes and disease?
S Sivaprasad et al.
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY (2005)
Classification of fundus autofluorescence patterns in early age-related macular disease
A Bindewald et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
The retinal pigment epithelium in visual function
O Strauss
PHYSIOLOGICAL REVIEWS (2005)
Geldanamycin activates Hsp70 response and attenuates okadaic acid-induced cytotoxicity in human retinal pigment epithelial cells
K Kaarniranta et al.
MOLECULAR BRAIN RESEARCH (2005)
A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration
GS Hageman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
RPE lipofuscin and its role in retinal-pathobiology
JR Sparrow et al.
EXPERIMENTAL EYE RESEARCH (2005)
Complement factor H polymorphism in age-related macular degeneration
RJ Klein et al.
SCIENCE (2005)
Complement factor H polymorphism and age-related macular degeneration
AO Edwards et al.
SCIENCE (2005)
Complement factor H variant increases the risk of age-related macular degeneration
JL Haines et al.
SCIENCE (2005)
Intracellular protein degradation: from a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting
A Ciechanover
CELL DEATH AND DIFFERENTIATION (2005)
Receptor for advanced glycation end products and age-related macular degeneration
KA Howes et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2004)
Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation
ML Seibenhener et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Neuroprotective and antiangiogenic actions of PEDF in the eye: molecular targets and therapeutic potential
CJ Barnstable et al.
PROGRESS IN RETINAL AND EYE RESEARCH (2004)
Lipofuscin
A Terman et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Innate immunity in the retina: Toll-like receptor (TLR) signaling in human retinal pigment epithelial cells
MV Kumar et al.
JOURNAL OF NEUROIMMUNOLOGY (2004)
Toll-like receptor 4 (TLR4) of retinal pigment epithelial cells participates in transmembrane signaling in response to photoreceptor outer segments
AL Kindzelskii et al.
JOURNAL OF GENERAL PHYSIOLOGY (2004)
Retinal pigment epithelial phagocytosis and metabolism differ from those of macrophages
EU Irschick et al.
OPHTHALMIC RESEARCH (2004)
Association of apolipoprotein E alleles with susceptibility to age-related macular degeneration in a large cohort from a single center
S Zareparsi et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2004)
Increased expression of p62 in expanded polyglutamine-expressing cells and its association with polyglutamine inclusions
U Nagaoka et al.
JOURNAL OF NEUROCHEMISTRY (2004)
The biology of VEGF and its receptors
N Ferrara et al.
NATURE MEDICINE (2003)
Age-related macular degeneration: Etiology, pathogenesis, and therapeutic strategies
J Ambati et al.
SURVEY OF OPHTHALMOLOGY (2003)
Vascular endothelial growth factor upregulates pigment epithelium-derived factor expression via VEGFR-1 in human retinal pigment epithelial cells
K Ohno-Matsui et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
RPE CD 14 immunohistochemical, genetic, and functional expression
VM Elner et al.
EXPERIMENTAL EYE RESEARCH (2003)
Drusen proteome analysis: An approach to the etiology of age-related macular degeneration
JW Crabb et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
The role of apoptosis in age-related macular degeneration
JL Dunaief et al.
ARCHIVES OF OPHTHALMOLOGY (2002)
Cytoplasmic dynein/dynactin mediates the assembly of aggresomes
JA Johnston et al.
CELL MOTILITY AND THE CYTOSKELETON (2002)
Early accumulation of p62 in neurofibrillary tangles in Alzheimer's disease: possible role in tangle formation
E Kuusisto et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2002)
Age-related maculopathy: pathogenetic features and new treatment modalities
PV Algvere et al.
ACTA OPHTHALMOLOGICA SCANDINAVICA (2002)
Protein folding - Molecular chaperones in the cytosol: from nascent chain to folded protein
FU Hartl et al.
SCIENCE (2002)
p62 is a common component of cytoplasmic inclusions in protein aggregation diseases
K Zatloukal et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Regulation of apoptosis by the ubiquitin and proteasome pathway
C Wojcik
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2002)
Complement activation and inflammatory processes in drusen formation and age related macular degeneration
LV Johnson et al.
EXPERIMENTAL EYE RESEARCH (2001)
An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration
GS Hageman et al.
PROGRESS IN RETINAL AND EYE RESEARCH (2001)
Local cellular sources of apolipoprotein E in the human retina and retinal pigmented epithelium: Implications for the process of drusen formation
DH Anderson et al.
AMERICAN JOURNAL OF OPHTHALMOLOGY (2001)
Risk factors for age related macular degeneration -: Pooled findings from three continents
W Smith et al.
OPHTHALMOLOGY (2001)
Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2) - A reassessment using novel receptor-specific vascular endothelial growth factor mutants
H Gille et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Ubiquitin-binding protein p62 expression is induced during apoptosis and proteasomal inhibition in neuronal cells
E Kuusisto et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Aggresomes, inclusion bodies and protein aggregation
RR Kopito
TRENDS IN CELL BIOLOGY (2000)
The role of oxidative stress in the pathogenesis of age-related macular degeneration
S Beatty et al.
SURVEY OF OPHTHALMOLOGY (2000)
Share Paper
