Journal
ACTA OPHTHALMOLOGICA
Volume 89, Issue 4, Pages E315-E319Publisher
WILEY-BLACKWELL
DOI: 10.1111/j.1755-3768.2010.02097.x
Keywords
amnion; amniotic membrane transplantation; cornea; corneal injury
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Funding
- Heilongjiang Provincial Department of Education [11541218, 2009.1-2011.12]
- Natural Science Foundation of Heilongjiang Province, China [D201052]
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Purpose: To determine whether amniotic membrane homogenate is as effective in healing corneal damage as amniotic membrane transplantation in a rabbit model. Method: The rabbits were divided into three groups. The cornea of one eye in each rabbit was incised resulting in a defect of approximately 8 mm in diameter. Amniotic membrane transplantation was performed in the first group, and amnion homogenate was administered four times a day in the second group. The third group was the control group. Results: There were no differences in the diameter of the defects and the rate of corneal growth between the amnion transplant group and the amnion homogenate group. Conclusion: Amnion homogenate is as effective as transplanted amniotic membrane in promoting corneal healing in a rabbit model.
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