Related references
Note: Only part of the references are listed.Expression of LRIG1 is associated with good prognosis and human papillomavirus status in oropharyngeal cancer
D. Lindquist et al.
BRITISH JOURNAL OF CANCER (2014)
Loss of LRIG1 Locus Increases Risk of Early and Late Relapse of Stage I/II Breast Cancer
Patricia A. Thompson et al.
CANCER RESEARCH (2014)
LRIG1 inhibits STAT3-dependent inflammation to maintain corneal homeostasis
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JOURNAL OF CLINICAL INVESTIGATION (2014)
Cbl-independent degradation of Met: ways to avoid agonism of bivalent Met-targeting antibody
J. M. Lee et al.
ONCOGENE (2014)
LRIG1 modulates aggressiveness of head and neck cancers by regulating EGFR-MAPK-SPHK1 signaling and extracellular matrix remodeling
J. J-C Sheu et al.
ONCOGENE (2014)
LRIG1 as a Potential Novel Marker for Neoplastic Transformation in Ocular Surface Squamous Neoplasia
Maho Nagata et al.
PLOS ONE (2014)
LRIG2 Mutations Cause Urofacial Syndrome
Helen M. Stuart et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2013)
Gambogic acid induces EGFR degradation and Akt/mTORC1 inhibition through AMPK dependent-LRIG1 upregulation in cultured U87 glioma cells
Xin-yao He et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
LRIG1 dictates the chemo-sensitivity of temozolomide (TMZ) in U251 glioblastoma cells via down-regulation of EGFR/topoisomerase-2/Bcl-2
Xu-chen Qi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
LRIG1 is a triple threat: ERBB negative regulator, intestinal stem cell marker and tumour suppressor
Y. Wang et al.
BRITISH JOURNAL OF CANCER (2013)
Leucine-rich Repeat and Immunoglobulin Domain-containing Protein-1 (Lrigl) Negative Regulatory Action toward ErbB Receptor Tyrosine Kinases Is Opposed by Leucine-rich Repeat and Immunoglobulin Domain-containing Protein 3 (Lrig3)
Hanine Rafidi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and pre-invasive squamous cell carcinoma development
Liwen Lu et al.
JOURNAL OF PATHOLOGY (2013)
The soluble form of the tumor suppressor Lrig1 potently inhibits in vivo glioma growth irrespective of EGF receptor status
Mikael Johansson et al.
NEURO-ONCOLOGY (2013)
Lrig2-Deficient Mice Are Protected against PDGFB-Induced Glioma
Veronica Rondahl et al.
PLOS ONE (2013)
Expression of EGFR and LRIG proteins in oesophageal carcinoma with emphasis on patient survival and cellular chemosensitivity
Xuping Wu et al.
ACTA ONCOLOGICA (2012)
Transcription factor co-localization patterns affect human cell type-specific gene expression
Dennis Wang et al.
BMC GENOMICS (2012)
LRIG1 Modulates Cancer Cell Sensitivity to Smac Mimetics by Regulating TNFα Expression and Receptor Tyrosine Kinase Signaling
Longchuan Bai et al.
CANCER RESEARCH (2012)
The Pan-ErbB Negative Regulator Lrig1 Is an Intestinal Stem Cell Marker that Functions as a Tumor Suppressor
Anne E. Powell et al.
CELL (2012)
Immunohistochemical analysis of LRIG proteins in meningiomas: correlation between estrogen receptor status and LRIG expression
Soma Ghasimi et al.
JOURNAL OF NEURO-ONCOLOGY (2012)
Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling
Vivian W. Y. Wong et al.
NATURE CELL BIOLOGY (2012)
Paracrine regulation of growth factor signaling by shed leucine-rich repeats and immunoglobulin-like domains 1
Wei Yi et al.
EXPERIMENTAL CELL RESEARCH (2011)
LRIG1 and the liar paradox in prostate cancer: a study of the expression and clinical significance of LRIG1 in prostate cancer
Marcus Thomasson et al.
INTERNATIONAL JOURNAL OF CANCER (2011)
Lrig1 Is an Estrogen-Regulated Growth Suppressor and Correlates with Longer Relapse-Free Survival in ERα-Positive Breast Cancer
Sheryl R. Krig et al.
MOLECULAR CANCER RESEARCH (2011)
LRIG2 in contrast to LRIG1 predicts poor survival in early-stage squamous cell carcinoma of the uterine cervix
Hakan Hedman et al.
ACTA ONCOLOGICA (2010)
Identifying common prognostic factors in genomic cancer studies: A novel index for censored outcomes
Sigrid Rouam et al.
BMC BIOINFORMATICS (2010)
Vertebrate Lrig3-ErbB Interactions Occur In Vitro but Are Unlikely to Play a Role in Lrig3-Dependent Inner Ear Morphogenesis
Victoria E. Abraira et al.
PLOS ONE (2010)
Caenorhabditis elegans SMA-10/LRIG Is a Conserved Transmembrane Protein that Enhances Bone Morphogenetic Protein Signaling
Tina L. Gumienny et al.
PLOS GENETICS (2010)
Downregulation of LRIG2 expression by RNA interference inhibits glioblastoma cell (GL15) growth, causes cell cycle redistribution, increases cell apoptosis and enhances cell adhesion and invasion in vitro
Baofeng Wang et al.
CANCER BIOLOGY & THERAPY (2009)
Chromosome 3p12.3-p14.2 and 3q26.2-q26.32 Are Genomic Markers for Prognosis of Advanced Nasopharyngeal Carcinoma
Jim Jinn-Chyuan Sheu et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2009)
Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epidermis
Kim B. Jensen et al.
CELL STEM CELL (2009)
Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo
Shunsaku Homma et al.
GENE EXPRESSION PATTERNS (2009)
Upregulation of LRIG1 suppresses malignant glioma cell growth by attenuating EGFR activity
Fei Ye et al.
JOURNAL OF NEURO-ONCOLOGY (2009)
Current smoking-specific gene expression signature in normal bronchial epithelium is enhanced in squamous cell lung cancer
Mirjam C. Boelens et al.
JOURNAL OF PATHOLOGY (2009)
Cytoplasmic LRIG2 expression is associated with poor oligodendroglioma patient survival
Camilla Holmlund et al.
NEUROPATHOLOGY (2009)
Investigating the Targets of MIR-15a and MIR-16-1 in Patients with Chronic Lymphocytic Leukemia (CLL)
Katy Hanlon et al.
PLOS ONE (2009)
Co-incidental increase in gene copy number of ERBB2 and LRIG1 in breast cancer
Ingrid Ljuslinder et al.
BREAST CANCER RESEARCH (2009)
A stem cell gene expression profile of human squamous cell carcinomas
Kim B. Jensen et al.
CANCER LETTERS (2008)
Suppression of the Negative Regulator LRIG1 Contributes to ErbB2 Overexpression in Breast Cancer
Jamie K. Miller et al.
CANCER RESEARCH (2008)
Lrig3 regulates neural crest formation in Xenopus by modulating Fgf and Wnt signaling pathways
Hui Zhao et al.
DEVELOPMENT (2008)
Cross-repressive interactions between Lrig3 and netrin 1 shape the architecture of the inner ear
Victoria E. Abraira et al.
DEVELOPMENT (2008)
LRIG1 and squamous epithelial uterine cervical cancer:: correlation to prognosis, other tumor markers, sex steroid hormones, and smoking
A. K. Lindstrom et al.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER (2008)
Redistribution of LRIG proteins in psoriasis
Terese Karlsson et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2008)
Lrig1 is an endogenous inhibitor of ret receptor tyrosine kinase activation, downstream signaling, and biological responses to GDNF
Fernanda Ledda et al.
JOURNAL OF NEUROSCIENCE (2008)
LRIG1 negatively regulates the oncogenic EGF receptor mutant EGFRvIII
M. A. Stutz et al.
ONCOGENE (2008)
LRIG1 is a novel negative regulator of the Met receptor and opposes met and Her2 synergy
David L. Shattuck et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
LRIG-inhibitors of growth factor signalling - double-edged swords in human cancer?
Hakan Hedman et al.
EUROPEAN JOURNAL OF CANCER (2007)
A soluble ectodomain of LRIG1 inhibits cancer cell growth by attenuating basal and ligand-dependent EGFR activity
S. Goldoni et al.
ONCOGENE (2007)
LRIG1 expression in colorectal cancer
Ingrid Ljuslinder et al.
ACTA ONCOLOGICA (2007)
LRIG1, a candidate tumour-suppressor gene in human bladder cancer cell line BIU87
Wei-Min Yang et al.
BJU INTERNATIONAL (2006)
Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence
Kim B. Jensen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Perinuclear leucine-rich repeats and immunoglobulin-like domain proteins (LRIG1-3) as prognostic indicators in astrocytic tumors
DS Guo et al.
ACTA NEUROPATHOLOGICA (2006)
LRIG-1 provides a novel prognostic predictor in squamous cell carcinoma of the skin: Immunohistochemical analysis for 38 cases
A Tanemura et al.
DERMATOLOGIC SURGERY (2005)
Increased copy number at 3p14 in breast cancer
I Ljuslinder et al.
BREAST CANCER RESEARCH (2005)
LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation
G Gur et al.
EMBO JOURNAL (2004)
The LRIG gene family has three vertebrate paralogs widely expressed in human and mouse tissues and a homolog in Ascidiacea
DS Guo et al.
GENOMICS (2004)
The leucine-rich repeat protein LRIG1 is a negative regulator of ErbB family receptor tyrosine kinases
MB Laederich et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Characterization and tissue-specific expression of human LRIG2
C Holmlund et al.
GENE (2004)
LRIGI and epidermal growth factor receptor in renal cell carcinoma: a quantitative RT-PCR and immunohistochemical analysis
M Thomasson et al.
BRITISH JOURNAL OF CANCER (2003)
Targeted disruption of LIG-1 gene results in psoriasiform epidermal hyperplasia
Y Suzuki et al.
FEBS LETTERS (2002)
Is LRIG1 a tumour suppressor gene at chromosome 3p14.3?
H Hedman et al.
ACTA ONCOLOGICA (2002)
Cloning, characterization, and expression of human LIG1
J Nilsson et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)