Journal
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
Volume 92, Issue 12, Pages 1353-1360Publisher
WILEY
DOI: 10.1111/aogs.12249
Keywords
Pregnancy; routine ultrasound; third trimester; small-for-gestational-age; large-for-gestational-age; intrauterine growth restriction; perinatal outcome
Categories
Funding
- National Center for Fetal Medicine, Department of Obstetrics and Gynecology, St Olav's Hospital, Trondheim University Hospital
- Department of Laboratory Medicine Children's and Women's Health, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway
Ask authors/readers for more resources
ObjectiveTo compare detection rates of small-for-gestational-age fetuses, large-for-gestational-age fetuses, congenital anomalies and adverse perinatal outcomes in pregnancies randomized to third-trimester routine ultrasound or ultrasound on clinical indication. DesignRandomized controlled trial. SettingNational Center for Fetal Medicine in Norway between 1989 and 1992. PopulationA total of 6780 pregnancies from a non-selected population. MethodsTwo routine ultrasound examinations at 18 and 33weeks were compared with routine ultrasound at 18weeks and ultrasound on clinical indication. Suspected small-for-gestational-age fetuses were followed with serial scans and cardiotocography. Doppler ultrasound was not used. Main outcome measuresDetection rates of small-for-gestational-age and large-for-gestational-age fetuses, congenital anomalies and adverse perinatal outcomes. ResultsThird trimester routine ultrasound improved detection rates of small-for-gestational-age fetuses from 46 to 80%, but overall perinatal morbidity and mortality remained unchanged. Detection of large-for-gestational-age fetuses increased from 36 to 91%. There was a significant increase of induction of labor and elective cesarean sections due to suspected small-for-gestational-age and a significant decrease of induction of labor and elective cesarean sections due to suspected large-for-gestational-age in the study group; there were no other differences regarding intervention. The detection rate of congenital anomalies was 56%, with no significant difference between the groups. ConclusionsRoutine use of third-trimester routine ultrasound increased detection rates of small-for-gestational-age and large-for-gestational-age fetuses. This did not alter perinatal outcomes. Third-trimester ultrasound screening should not be rejected before a policy of adding Doppler surveillance to the high-risk group identified has been investigated further.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available