Related references
Note: Only part of the references are listed.Small Molecule Inhibition of GDC-0449 Refractory Smoothened Mutants and Downstream Mechanisms of Drug Resistance
Gerrit J. P. Dijkgraaf et al.
CANCER RESEARCH (2011)
Upregulation of E2F1 in cerebellar neuroprogenitor cells and cell cycle arrest during postnatal brain development
Daniela E. Suzuki et al.
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL (2011)
FSTL5 Is a Marker of Poor Prognosis in Non-WNT/Non-SHH Medulloblastoma
Marc Remke et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Can Clues from Evolution Unlock the Molecular Development of the Cerebellum?
Thomas Butts et al.
MOLECULAR NEUROBIOLOGY (2011)
Cilia in the CNS: The Quiet Organelle Claims Center Stage
Angeliki Louvi et al.
NEURON (2011)
Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases
Marie Cargnello et al.
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2011)
Mitogenic Sonic hedgehog signaling drives E2F1-dependent lipogenesis in progenitor cells and medulloblastoma
B. Bhatia et al.
ONCOGENE (2011)
Divergent functions for eIF4E and S6 kinase by sonic hedgehog mitogenic signaling in the developing cerebellum
L. A. Mainwaring et al.
ONCOGENE (2011)
Fenretinide-dependent upregulation of death receptors through ASK1 and p38α enhances death receptor ligand-induced cell death in Ewing's sarcoma family of tumours
D. E. White et al.
BRITISH JOURNAL OF CANCER (2010)
β-Arrestin-1 links mitogenic sonic hedgehog signaling to the cell cycle exit machinery in neural precursors
Susana R. Parathath et al.
CELL CYCLE (2010)
p38α Is Required for Ovarian Cancer Cell Metabolism and Survival
Antonio Matrone et al.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER (2010)
Heterozygosity for Pten Promotes Tumorigenesis in a Mouse Model of Medulloblastoma
Robert C. Castellino et al.
PLOS ONE (2010)
Interfering with Resistance to Smoothened Antagonists by Inhibition of the PI3K Pathway in Medulloblastoma
Silvia Buonamici et al.
SCIENCE TRANSLATIONAL MEDICINE (2010)
Tuberous Sclerosis Complex Suppression in Cerebellar Development and Medulloblastoma: Separate Regulation of Mammalian Target of Rapamycin Activity and p27Kip1 Localization
Bobby Bhatia et al.
CANCER RESEARCH (2009)
The miR-17/92 Polycistron Is Up-regulated in Sonic Hedgehog-Driven Medulloblastomas and Induced by N-myc in Sonic Hedgehog-Treated Cerebellar Neural Precursors
Paul A. Northcott et al.
CANCER RESEARCH (2009)
Hedgehog signalling: Emerging evidence for non-canonical pathways
Dagan Jenkins
CELLULAR SIGNALLING (2009)
SHH Pathway and Cerebellar Development
Catherine Vaillant et al.
CEREBELLUM (2009)
Medulloblastomas: a correlative study of MIB-1 proliferation index along with expression of c-Myc, ERBB2, and anti-apoptotic proteins along with histological typing and clinical outcome
Prasenjit Das et al.
CHILDS NERVOUS SYSTEM (2009)
Hedgehog Target Genes: Mechanisms of Carcinogenesis Induced by Aberrant Hedgehog Signaling Activation
Y. Katoh et al.
CURRENT MOLECULAR MEDICINE (2009)
The p38 MAPK inhibitors for the treatment of inflammatory diseases and cancer
Hae-Young Yong et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2009)
YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation
Africa Fernandez-L et al.
GENES & DEVELOPMENT (2009)
Non-Classical P38 Map Kinase Functions: Cell Cycle Checkpoints and Survival
Tina M. Thornton et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2009)
Smoothened Mutation Confers Resistance to a Hedgehog Pathway Inhibitor in Medulloblastoma
Robert L. Yauch et al.
SCIENCE (2009)
Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma
Ulrich Schueller et al.
CANCER CELL (2008)
Medulloblastoma can be initiated by deletion of patched in lineage-restricted progenitors or stem cells
Zeng-Jie Yang et al.
CANCER CELL (2008)
The Smo/Smo model: Hedgehog-induced medulloblastoma with 90% incidence and leptomeningeal spread
Beryl A. Hatton et al.
CANCER RESEARCH (2008)
Insulin receptor substrate 1 is an effector of sonic hedgehog mitogenic signaling in cerebellar neural precursors
Susana R. Parathath et al.
DEVELOPMENT (2008)
Primary cilia are required for cerebellar development and Shh-dependent expansion of progenitor pool
N. Spassky et al.
DEVELOPMENTAL BIOLOGY (2008)
Fibroblast growth factor blocks Sonic hedgehog signaling in neuronal precursors and tumor cells
Marie P. Fogarty et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Neurotoxicity of domoic acid in cerebellar granule neurons in a genetic model of glutathione deficiency
G. Giordano et al.
MOLECULAR PHARMACOLOGY (2006)
The level of sonic hedgehog signaling regulates the complexity of cerebellar foliation
JD Corrales et al.
DEVELOPMENT (2006)
Neural precursor cycling at sonic speed - N-Myc pedals, GSK-3 brakes
PS Knoepfler et al.
CELL CYCLE (2006)
Generation and characterization of p38β (MAPK11) gene-targeted mice
VA Beardmore et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
PBK/TOPK, a proliferating neural progenitor-specific mitogen-activated protein kinase kinase
JD Dougherty et al.
JOURNAL OF NEUROSCIENCE (2005)
Prognostic significance of apoptosis in medulloblastoma
J Pizem et al.
NEUROSCIENCE LETTERS (2005)
Loss of patched and disruption of granule cell development in a pre-neoplastic stage of medulloblastoma
TG Oliver et al.
DEVELOPMENT (2005)
Insulin-like growth factor II is involved in the proliferation control of medulloblastoma and its cerebellar precursor cells
W Hartmann et al.
AMERICAN JOURNAL OF PATHOLOGY (2005)
Cellular and genetic regulation of the development of the cerebellar system
C Sotelo
PROGRESS IN NEUROBIOLOGY (2004)
Differences in spatial learning comparing transgenic p75 knockout, New Zealand Black, C57BL/6, and Swiss webster mice
JW Wright et al.
BEHAVIOURAL BRAIN RESEARCH (2004)
Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors
AM Kenney et al.
DEVELOPMENT (2004)
Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum
PM Lewis et al.
DEVELOPMENTAL BIOLOGY (2004)
The SmoA1 mouse model reveals that notch signaling is critical for the growth and survival of sonic hedgehog-induced medulloblastomas
AR Hallahan et al.
CANCER RESEARCH (2004)
Transcriptional profiling of the Sonic hedgehog response: A critical role for N-myc in proliferation of neuronal precursors
TG Oliver et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors
AM Kenney et al.
DEVELOPMENT (2003)
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
GL Johnson et al.
SCIENCE (2002)
Medulloblastoma growth inhibition by Hedgehog pathway blockade
DM Berman et al.
SCIENCE (2002)
Identification of genes expressed with temporal-spatial restriction to developing cerebellar neuron precursors by a functional genomic approach
Q Zhao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Vascular smooth muscle cell proliferation requires both p38 and BMK1 MAP kinases
M Zhao et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2002)
Sonic hedgehog promotes G1 cyclin expression and sustained cell cycle progression in mammalian neuronal precursors
AM Kenney et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Share Paper
