4.6 Review

The genetics and neuropathology of Alzheimer's disease

Related references

Note: Only part of the references are listed.
Review Genetics & Heredity

Five Years of GWAS Discovery

Peter M. Visscher et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2012)

Article Immunology

Complement receptor 1 (CR1) and Alzheimer's disease

Helen Crehan et al.

IMMUNOBIOLOGY (2012)

Article Multidisciplinary Sciences

ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models

Paige E. Cramer et al.

SCIENCE (2012)

Article Clinical Neurology

CR1 Is Associated with Amyloid Plaque Burden and Age-Related Cognitive Decline

Lori B. Chibnik et al.

ANNALS OF NEUROLOGY (2011)

Review Neurosciences

Amyloid Precursor Protein Processing and Alzheimer's Disease

Richard J. O'Brien et al.

ANNUAL REVIEW OF NEUROSCIENCE, VOL 34 (2011)

Article Clinical Neurology

Meta-analysis of the Association Between Variants in SORL1 and Alzheimer Disease

Christiane Reitz et al.

ARCHIVES OF NEUROLOGY (2011)

Review Biochemistry & Molecular Biology

Membrane shaping by the Bin/amphiphysin/Rvs (BAR) domain protein superfamily

Yijian Rao et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2011)

Article Cell Biology

Endosomal clathrin drives actin accumulation at the immunological synapse

Carmen Calabia-Linares et al.

JOURNAL OF CELL SCIENCE (2011)

Article Medicine, Research & Experimental

Expression Profiling of the Ephrin (EFN) and Eph Receptor (EPH) Family of Genes in Atherosclerosis-related Human Cells

A. Sakamoto et al.

JOURNAL OF INTERNATIONAL MEDICAL RESEARCH (2011)

Article Clinical Neurology

Mind the IGAP

David Holmes

LANCET NEUROLOGY (2011)

Article Biochemistry & Molecular Biology

APOE and Alzheimer disease: a major gene with semi-dominant inheritance

E. Genin et al.

MOLECULAR PSYCHIATRY (2011)

Article Genetics & Heredity

Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

Guenter U. Hoeglinger et al.

NATURE GENETICS (2011)

Article Geriatrics & Gerontology

TOMM40 poly-T repeat lengths, age of onset and psychosis risk in Alzheimer disease

Su Hee Chu et al.

NEUROBIOLOGY OF AGING (2011)

News Item Multidisciplinary Sciences

Disease Risk Links To Gene Regulation

Elizabeth Pennisi

SCIENCE (2011)

Review Biochemistry & Molecular Biology

Genetic evidence for the involvement of lipid metabolism in Alzheimer's disease

Lesley Jones et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2010)

Review Biochemistry & Molecular Biology

Cholesterol-related genes in Alzheimer's disease

M. Axel Wollmer

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2010)

Article Medicine, General & Internal

Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease

Sudha Seshadri et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2010)

Article Neurosciences

Systematic Analysis of Candidate Genes for Alzheimer's Disease in a French, Genome-Wide Association Study

Geoffroy Laumet et al.

JOURNAL OF ALZHEIMERS DISEASE (2010)

Article Neurosciences

The CALHM1 P86L Polymorphism is a Genetic Modifier of Age at Onset in Alzheimer's Disease: a Meta-Analysis Study

Jean-Charles Lambert et al.

JOURNAL OF ALZHEIMERS DISEASE (2010)

Article Cell Biology

Activation of EphA receptors on CD4+CD45RO+ memory cells stimulates migration

H. L. Holen et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2010)

Article Clinical Neurology

Clinical, Neuropathologic, and Biochemical Profile of the Amyloid Precursor Protein 1716F Mutation

Cristina Guardia-Laguarta et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2010)

Review Clinical Neurology

γ-secretases: from cell biology to therapeutic strategies

Bruno A. Bergmans et al.

LANCET NEUROLOGY (2010)

Article Multidisciplinary Sciences

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

Kiran Musunuru et al.

NATURE (2010)

Article Multidisciplinary Sciences

Biological, clinical and population relevance of 95 loci for blood lipids

Tanya M. Teslovich et al.

NATURE (2010)

Article Genetics & Heredity

A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease

A. D. Roses et al.

PHARMACOGENOMICS JOURNAL (2010)

Article Genetics & Heredity

PCDH11X variation is not associated with late-onset Alzheimer disease susceptibility

Gary W. Beecham et al.

PSYCHIATRIC GENETICS (2010)

Article Multidisciplinary Sciences

γ-Secretase Gene Mutations in Familial Acne Inversa

Baoxi Wang et al.

SCIENCE (2010)

Review Genetics & Heredity

The pursuit of susceptibility genes for Alzheimer's disease: progress and prospects

Kristel Sleegers et al.

TRENDS IN GENETICS (2010)

Article Genetics & Heredity

Genome-wide Association Study Implicates a Chromosome 12 Risk Locus for Late-Onset Alzheimer Disease

Gary W. Beecham et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2009)

Article Neurosciences

Association of SORL1 gene variants with Alzheimer's disease

Heike Koelsch et al.

BRAIN RESEARCH (2009)

Review Neurosciences

Clusterin: A forgotten player in Alzheimer's disease

Tapio Nuutinen et al.

BRAIN RESEARCH REVIEWS (2009)

Review Biochemistry & Molecular Biology

The Vps10p-domain receptor family

Guido Hermey

CELLULAR AND MOLECULAR LIFE SCIENCES (2009)

Review Neurosciences

Synapse development and plasticity: roles of ephrin/Eph receptor signaling

Kwok-On Lai et al.

CURRENT OPINION IN NEUROBIOLOGY (2009)

Review Pediatrics

Molecular genetic analysis of podocyte genes in focal segmental glomerulosclerosis-a review

M. M. Lowik et al.

EUROPEAN JOURNAL OF PEDIATRICS (2009)

Article Cell Biology

EphA1 interacts with integrin-linked kinase and regulates cell morphology and motility

Tohru Yamazaki et al.

JOURNAL OF CELL SCIENCE (2009)

Article Biochemistry & Molecular Biology

Apolipoprotein E: structure determines function, from atherosclerosis to Alzheimer's disease to AIDS

Robert W. Mahley et al.

JOURNAL OF LIPID RESEARCH (2009)

Article Clinical Neurology

Identification of independent APP locus duplication in Japanese patients with early-onset Alzheimer disease

K. Kasuga et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2009)

Article Dermatology

Hidradenitis suppurativa

J. Revuz

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2009)

Article Genetics & Heredity

Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease

Minerva M. Carrasquillo et al.

NATURE GENETICS (2009)

Article Genetics & Heredity

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

Jean-Charles Lambert et al.

NATURE GENETICS (2009)

Article Geriatrics & Gerontology

SORL1 haplotypes modulate risk of Alzheimer's disease in Chinese

E. K. Tan et al.

NEUROBIOLOGY OF AGING (2009)

Article Genetics & Heredity

Assessment of Alzheimer's disease case-control associations using family-based methods

Brit-Maren M. Schjeide et al.

NEUROGENETICS (2009)

Review Neurosciences

The Role of Apolipoprotein E in Alzheimer's Disease

Jungsu Kim et al.

NEURON (2009)

Article Neurosciences

SORL1 is genetically associated with Alzheimer disease in a Japanese population

Ryo Kimura et al.

NEUROSCIENCE LETTERS (2009)

Article Genetics & Heredity

Genome-wide Association Analysis Reveals Putative Alzheimer's Disease Susceptibility Loci in Addition to APOE

Lars Bertram et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2008)

Article Multidisciplinary Sciences

Basic and Clinical Immunology of Siglecs

Stephan von Gunten et al.

YEAR IN IMMUNOLOGY 2008 (2008)

Article Genetics & Heredity

A genome-wide association study for late-onset Alzheimer's disease using DNA pooling

Richard Abraham et al.

BMC MEDICAL GENOMICS (2008)

Review Biochemistry & Molecular Biology

Role of ATP-binding cassette transporters in brain lipid transport and neurological disease

Woojin Scott Kim et al.

JOURNAL OF NEUROCHEMISTRY (2008)

Article Neurosciences

SORL1 variants and risk of late-onset Alzheimer's disease

Yonghong Li et al.

NEUROBIOLOGY OF DISEASE (2008)

Article Neurosciences

No association of SORL1 SNPs with Alzheimer's disease

Ryan L. Minster et al.

NEUROSCIENCE LETTERS (2008)

Review Cell Biology

Membrane traffic and muscle: Lessons from human disease

James J. Dowling et al.

TRAFFIC (2008)

Article Cell Biology

Cell-cell signaling via Eph receptors and ephrins

Juha-Pekka Himanen et al.

CURRENT OPINION IN CELL BIOLOGY (2007)

Article Cell Biology

Endocytosis: clathrin-mediated membrane budding

Ernst J. Ungewickell et al.

CURRENT OPINION IN CELL BIOLOGY (2007)

Article Genetics & Heredity

A genomewide screen for late-onset Alzheimer disease in a genetically isolated Dutch population

Fan Liu et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2007)

Article Neurosciences

GAB2 alleles modify Alzheimer's risk in APOE ε4 carriers

Eric M. Reiman et al.

NEURON (2007)

Article Oncology

Meta-analysis of BRCA1 and BRCA2 penetrance

Sining Chen et al.

JOURNAL OF CLINICAL ONCOLOGY (2007)

Article Genetics & Heredity

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

Ekaterina Rogaeva et al.

NATURE GENETICS (2007)

Article Multidisciplinary Sciences

The presenilin hypothesis of Alzheimer's disease: Evidence for a loss-of-function pathogenic mechanism

Jie Shen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Review Immunology

Siglecs and their roles in the immune system

Paul R. Crocker et al.

NATURE REVIEWS IMMUNOLOGY (2007)

Article Education, Special

Dementia and mortality in persons with Down's syndrome

A. Coppus et al.

JOURNAL OF INTELLECTUAL DISABILITY RESEARCH (2006)

Article Biochemistry & Molecular Biology

ABCA7 expression is regulated by cellular cholesterol through the SREBP2 pathway and associated with phagocytosis

Noriyuki Iwamoto et al.

JOURNAL OF LIPID RESEARCH (2006)

Review Biochemistry & Molecular Biology

Putative dual role of ephrin-Eph receptor interactions in inflammation

Andrei I. Ivanov et al.

IUBMB LIFE (2006)

Review Microbiology

The BAR domain proteins: Molding membranes in fission, fusion, and phagy

G Ren et al.

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2006)

Article Multidisciplinary Sciences

Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein

OM Andersen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Review Cell Biology

EPH receptor signalling casts a wide net on cell behaviour

EB Pasquale

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)

Article Clinical Neurology

A mutant PSEN1 causes dementia with Lewy bodies and variant Alzheimer's disease

A Ishikawa et al.

ANNALS OF NEUROLOGY (2005)

Article Genetics & Heredity

APOE and other loci affect age-at-onset in Alzheimer's disease families with PS2 mutation

EM Wijsman et al.

AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2005)

Article Neurosciences

Positional effects of presenilin-1 mutations on tau phosphorylation in cortical plaques

CE Shepherd et al.

NEUROBIOLOGY OF DISEASE (2004)

Article Geriatrics & Gerontology

Two novel presenilin-1 mutations (Y256S and Q222H) are associated with early-onset Alzheimer's disease

J Miklossy et al.

NEUROBIOLOGY OF AGING (2003)

Article Clinical Neurology

Apolipoprotein Eε4 modifies Alzheimer's disease onset in an E280A PS1 kindred

P Pastor et al.

ANNALS OF NEUROLOGY (2003)

Article Physiology

CD2-associated protein directly interacts with the actin cytoskeleton

S Lehtonen et al.

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2002)

Article Pathology

Dense-core senile plaques in the Flemish variant of Alzheimer's disease are vasocentric

S Kumar-Singh et al.

AMERICAN JOURNAL OF PATHOLOGY (2002)

Article Geriatrics & Gerontology

Dementia in people with Down's syndrome

J Tyrrell et al.

INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY (2001)

Article Hematology

LR11, a mosaic LDL receptor family member, mediates the uptake of ApoE-rich lipoproteins in vitro

K Taira et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2001)

Article Clinical Neurology

Variant Alzheimer disease with spastic paraparesis: Neuropathological phenotype

A Verkkoniemi et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2001)

Article Geriatrics & Gerontology

Distinguishable effects of Presenilin-1 and APP717 mutations on amyloid plaque deposition

K Ishii et al.

NEUROBIOLOGY OF AGING (2001)

Article Biochemistry & Molecular Biology

A pathogenic presenilin-1 deletion causes abberrant Aβ42 production in the absence of congophilic amyloid plaques

H Steiner et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Cardiac & Cardiovascular Systems

Eph receptors and ephrin ligands: Essential mediators of vascular development

RH Adams et al.

TRENDS IN CARDIOVASCULAR MEDICINE (2000)