Related references
Note: Only part of the references are listed.Tau Accumulation Causes Mitochondrial Distribution Deficits in Neurons in a Mouse Model of Tauopathy and in Human Alzheimer's Disease Brain
Katherine J. Kopeikina et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Mitochondrially localized PKA reverses mitochondrial pathology and dysfunction in a cellular model of Parkinson's disease
R. K. Dagda et al.
CELL DEATH AND DIFFERENTIATION (2011)
Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission
Jian Zhao et al.
EMBO JOURNAL (2011)
Calpain inhibitors: a survey of compounds reported in the patent and scientific literature
Isaac O. Donkor
EXPERT OPINION ON THERAPEUTIC PATENTS (2011)
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage
Maria Manczak et al.
HUMAN MOLECULAR GENETICS (2011)
Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage
Ulziibat Shirendeb et al.
HUMAN MOLECULAR GENETICS (2011)
The Mitochondrial Inner Membrane GTPase, Optic Atrophy 1 (Opa1), Restores Mitochondrial Morphology and Promotes Neuronal Survival following Excitotoxicity
Arezu Jahani-Asl et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Parkin Ubiquitinates Drp1 for Proteasome-dependent Degradation IMPLICATION OF DYSREGULATED MITOCHONDRIAL DYNAMICS IN PARKINSON DISEASE
Hongxia Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Direct Membrane Association Drives Mitochondrial Fission by the Parkinson Disease-associated Protein α-Synuclein
Ken Nakamura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Aberrant mitochondrial fission in neurons induced by protein kinase Cδ under oxidative stress conditions in vivo
Xin Qi et al.
MOLECULAR BIOLOGY OF THE CELL (2011)
The crystal structure of dynamin
Marijn G. J. Ford et al.
NATURE (2011)
α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation
Tim Bartels et al.
NATURE (2011)
During autophagy mitochondria elongate, are spared from degradation and sustain cell viability
Ligia C. Gomes et al.
NATURE CELL BIOLOGY (2011)
RALA and RALBP1 regulate mitochondrial fission at mitosis
David F. Kashatus et al.
NATURE CELL BIOLOGY (2011)
miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1
Jian-Xun Wang et al.
NATURE MEDICINE (2011)
Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity
Wenjun Song et al.
NATURE MEDICINE (2011)
Conformational changes in Dnm1 support a contractile mechanism for mitochondrial fission
Jason A. Mears et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
FK506 ameliorates cell death features in Huntington's disease striatal cell models
Tatiana R. Rosenstock et al.
NEUROCHEMISTRY INTERNATIONAL (2011)
A Transcriptomic Atlas of Mouse Neocortical Layers
T. Grant Belgard et al.
NEURON (2011)
Cdk5: Multitasking between physiological and pathological conditions
Joao P. Lopes et al.
PROGRESS IN NEUROBIOLOGY (2011)
ER Tubules Mark Sites of Mitochondrial Division
Jonathan R. Friedman et al.
SCIENCE (2011)
A Selective Inhibitor of Drp1, Mdivi-1, Increases Retinal Ganglion Cell Survival in Acute Ischemic Mouse Retina
Sang Woo Park et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2011)
Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations
Hsiuchen Chen et al.
CELL (2010)
Membrane Remodeling Induced by the Dynamin-Related Protein Drp1 Stimulates Bax Oligomerization
Sylvie Montessuit et al.
CELL (2010)
Inhibition of Drp1-dependent mitochondrial fragmentation and apoptosis by a polypeptide antagonist of calcineurin
G. M. Cereghetti et al.
CELL DEATH AND DIFFERENTIATION (2010)
Inhibiting Mitochondrial Fission Protects the Heart Against Ischemia/Reperfusion Injury
Sang-Bing Ong et al.
CIRCULATION (2010)
Mitochondrial fission and cristae disruption increase the response of cell models of Huntington's disease to apoptotic stimuli
Veronica Costa et al.
EMBO MOLECULAR MEDICINE (2010)
Different Pathways Lead to Mitochondrial Fragmentation During Apoptotic and Excitotoxic Cell Death in Primary Neurons
Kenneth W. Young et al.
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2010)
Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1
Yong-Yea Park et al.
JOURNAL OF CELL SCIENCE (2010)
S-Nitrosylation of Drp1 links excessive mitochondrial fission to neuronal injury in neurodegeneration
Tomohiro Nakamura et al.
MITOCHONDRION (2010)
Mitochondrial fission/fusion dynamics and apoptosis
Clare Sheridan et al.
MITOCHONDRION (2010)
Delayed Treatment with Systemic (S)-Roscovitine Provides Neuroprotection and Inhibits In Vivo CDK5 Activity Increase in Animal Stroke Models
Benedicte Menn et al.
PLOS ONE (2010)
Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease
Marta M. Lipinski et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
Derek P. Narendra et al.
PLOS BIOLOGY (2010)
SLP-2 is required for stress-induced mitochondrial hyperfusion
Daniel Tondera et al.
EMBO JOURNAL (2009)
MAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fission
Emelie Braschi et al.
EMBO REPORTS (2009)
Loss of Drp1 function alters OPA1 processing and changes mitochondrial membrane organization
Kristin Moepert et al.
EXPERIMENTAL CELL RESEARCH (2009)
Drp1 levels constitutively regulate mitochondrial dynamics and cell survival in cortical neurons
Takuma Uo et al.
EXPERIMENTAL NEUROLOGY (2009)
SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle
Claudia Figueroa-Romero et al.
FASEB JOURNAL (2009)
Ca2+-dependent regulation of mitochondrial dynamics by the Miro-Milton complex
Xingguo Liu et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2009)
Translocation of SenP5 from the Nucleoli to the Mitochondria Modulates DRP1-dependent Fission during Mitosis
Rodolfo Zunino et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice
Junko Wakabayashi et al.
JOURNAL OF CELL BIOLOGY (2009)
Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models
Craig Brooks et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease
Xinglong Wang et al.
JOURNAL OF NEUROSCIENCE (2009)
Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice
Naotada Ishihara et al.
NATURE CELL BIOLOGY (2009)
MICROGLIAL CLEARANCE FUNCTION IN HEALTH AND DISEASE
I. Napoli et al.
NEUROSCIENCE (2009)
Mitochondrial Fragmentation Is Involved in Methamphetamine-Induced Cell Death in Rat Hippocampal Neural Progenitor Cells
Changhai Tian et al.
PLOS ONE (2009)
Mitochondrial Alterations in PINK1 Deficient Cells Are Influenced by Calcineurin-Dependent Dephosphorylation of Dynamin-Related Protein 1
Anna Sandebring et al.
PLOS ONE (2009)
A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase
Kasturi Mitra et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Mechanistic Analysis of a Dynamin Effector
Laura L. Lackner et al.
SCIENCE (2009)
S-Nitrosylation of Drp1 Mediates β-Amyloid-Related Mitochondrial Fission and Neuronal Injury
Dong-Hyung Cho et al.
SCIENCE (2009)
Apoptotic Mechanisms After Cerebral Ischemia
Brad R. S. Broughton et al.
STROKE (2009)
The changing shape of mitochondrial apoptosis
Michal Wasilewski et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2009)
Animal models of Parkinson's disease progression
Gloria E. Meredith et al.
ACTA NEUROPATHOLOGICA (2008)
Mitofusin 2: A mitochondria-shaping protein with signaling roles beyond fusion
Olga Martins De Brito et al.
ANTIOXIDANTS & REDOX SIGNALING (2008)
High levels of Fis1, a pro-fission mitochondrial protein, trigger autophagy
Ligia C. Gomes et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2008)
Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization
Ann Cassidy-Stone et al.
DEVELOPMENTAL CELL (2008)
Dimer ribbons of ATP synthase shape the inner mitochondrial membrane
Mike Strauss et al.
EMBO JOURNAL (2008)
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
Gilad Twig et al.
EMBO JOURNAL (2008)
Selective Actions of Mitochondrial Fission/Fusion Genes on Metabolism-Secretion Coupling in Insulin-releasing Cells
Kyu-Sang Park et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The Spinocerebellar Ataxia 12 Gene Product and Protein Phosphatase 2A Regulatory Subunit Bβ2 Antagonizes Neuronal Survival by Promoting Mitochondrial Fission
Ruben K. Dagda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
CaM kinase lα-induced phosphorylation of Drp1 regulates mitochondrial morphology
Xiao-Jian Han et al.
JOURNAL OF CELL BIOLOGY (2008)
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
Derek Narendra et al.
JOURNAL OF CELL BIOLOGY (2008)
Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria
G. M. Cereghetti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Amyloid-β overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins
Xinglong Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Hindlimb gait defects due to motor axon loss and reduced distal muscles in a transgenic mouse model of Charcot-Marie-Tooth type 2A
Scott A. Detmer et al.
HUMAN MOLECULAR GENETICS (2008)
Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death
J. Thomas Cribbs et al.
EMBO REPORTS (2007)
Mitofusin 2 protects cerebellar granule neurons against injury-induced cell death
Arezu Jahani-Asl et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Mitochondrial fusion protects against neurodegeneration in the cerebellum
Hsiuchen Chen et al.
CELL (2007)
The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division
Mariusz Karbowski et al.
JOURNAL OF CELL BIOLOGY (2007)
Mitochondrial targeting of quinones: Therapeutic implications
Helena M. Cocheme et al.
MITOCHONDRION (2007)
Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death
Sylwia Wasiak et al.
JOURNAL OF CELL BIOLOGY (2007)
Mitochondrial dynamics in the regulation of neuronal cell death
Eric C. C. Cheung et al.
APOPTOSIS (2007)
A lethal defect of mitochondrial and peroxisomal fission
Hans R. Waterham et al.
NEW ENGLAND JOURNAL OF MEDICINE (2007)
Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission
Naoko Taguchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Cyclin-dependent kinase 5 is an upstream regulator of mitochondrial fission during neuronal apoptosis
K. Meuer et al.
CELL DEATH AND DIFFERENTIATION (2007)
Mitochondrial fission is an upstream and required event for Bax foci formation in response to nitric oxide in cortical neurons
H. Yuan et al.
CELL DEATH AND DIFFERENTIATION (2007)
Improved reperfusion and neuroprotection by creatine in a mouse model of stroke
Konstantin Prass et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2007)
The SUMO protease SENP5 is required to maintain mitochondrial morphology and function
Rodolfo Zunino et al.
JOURNAL OF CELL SCIENCE (2007)
Inhibiting the mitochondrial fission machinery does not prevent Bax/Bak-dependent apoptosis
Philippe A. Parone et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons
Mark J. Barsoum et al.
EMBO JOURNAL (2006)
Dysregulation of mitochondrial fusion and fission: an emerging concept in neurodegeneration
S Frank
ACTA NEUROPATHOLOGICA (2006)
Bax/Bak-dependent release promotes of DDP/TIMM8a promotes Drp1-mediated mitochondrial fission and mitoptosis during programmed cell death
D Arnoult et al.
CURRENT BIOLOGY (2005)
Oxidative stress in brain aging, neurodegenerative and vascular diseases: An overview
E Mariani et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2005)
Dnm1 forms spirals that are structurally tailored to fit mitochondria
E Ingerman et al.
JOURNAL OF CELL BIOLOGY (2005)
Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions
P Verstreken et al.
NEURON (2005)
Prevalence and incidence of Parkinson's disease in Europe
S von Campenhausen et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2005)
Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis
M Germain et al.
EMBO JOURNAL (2005)
Distinct mechanistic roles of calpain and caspase activation in neurodegeneration as revealed in mice overexpressing their specific inhibitors
M Higuchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Mitochondrial function and actin regulate dynamin-related protein 1-dependent mitochondrial fission
KJ De Vos et al.
CURRENT BIOLOGY (2005)
Cytoplasmic dynein regulates the subcellular distribution of mitochondria by controlling the recruitment of the fission factor dynamin-related protein-1
A Varadi et al.
JOURNAL OF CELL SCIENCE (2004)
The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses
Z Li et al.
CELL (2004)
Mitofusin 1 and 2 play distinct roles in mitochondrial fusion reactions via GTPase activity
N Ishihara et al.
JOURNAL OF CELL SCIENCE (2004)
Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A
S Züchner et al.
NATURE GENETICS (2004)
hFis1, a novel component of the mammalian mitochondrial fission machinery
DI James et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
HC Chen et al.
JOURNAL OF CELL BIOLOGY (2003)
Altered proteasomal function in sporadic Parkinson's disease
KS McNaught et al.
EXPERIMENTAL NEUROLOGY (2003)
A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis
L Scorrano et al.
DEVELOPMENTAL CELL (2002)
The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis
S Frank et al.
DEVELOPMENTAL CELL (2001)
Inter-mitochondrial complementation: Mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA
K Nakada et al.
NATURE MEDICINE (2001)
Human cells are protected from mitochondrial dysfunction by complementation of DNA products in fused mitochondria
T Ono et al.
NATURE GENETICS (2001)
Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy
C Delettre et al.
NATURE GENETICS (2000)
OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28
C Alexander et al.
NATURE GENETICS (2000)