4.4 Review

Hypertrophic olivary degeneration after surgical removal of cavernous malformations of the brain stem: report of four cases and review of the literature

Journal

ACTA NEUROCHIRURGICA
Volume 150, Issue 2, Pages 149-156

Publisher

SPRINGER WIEN
DOI: 10.1007/s00701-007-1470-0

Keywords

hypertrophic olivary degeneration; surgery; cavernous malformation; brainstem

Ask authors/readers for more resources

Background. Hypertrophic olivary degeneration (HOD) is a pathological phenomenon that occurs after injury to the dentato-olivary pathway. Its hallmarks include hypertrophy of the olive with increased T2 signal intensity on magnetic resonance imaging, and it often manifests with palatal tremor and oscillopsia clinically. Method. We report the cases of four patients who developed delayed HOD after surgical resection of pontine lesions. Findings. We discuss the anatomical and pathological details of this disease and review the few other reported cases of HOD after resection of lesions within the brainstem. Conclusions. HOD should be recognized as a possible complication of surgery within the brainstem and must be diagnosed promptly so that patients can be appropriately counseled and symptoms can be treated.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.4
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available