Journal
INFECTIOUS DISEASE CLINICS OF NORTH AMERICA
Volume 29, Issue 2, Pages 341-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.idc.2015.02.007
Keywords
Anaplasmosis; Human; Granulocytic; Diagnosis; Management
Categories
Funding
- NIH [R01AI44102]
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Human granulocytic anaplasmosis, a deer tick transmitted rickettsia] infection caused by Anaplasma phagocytophilum, is a common cause of undifferentiated fever in the northeast and upper Midwest United States. Patients are often initially diagnosed with a mild viral infection, and illness readily resolves in most cases. However, as many as 3% develop life-threatening complications and nearly 1% die from the infection. Although coinfections with Borrelia burgdorferi and Babesia microti occur, there is little evidence to suggest synergism of disease or a role for A phagocytophilum in chronic illness. No vaccine is available.
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