Journal
ACTA HAEMATOLOGICA
Volume 127, Issue 4, Pages 235-243Publisher
KARGER
DOI: 10.1159/000336241
Keywords
Alemtuzumab; Kaposi sarcoma; Pentostatin; Prolymphocytes; T cell prolymphocytic leukemia
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T cell prolymphocytic leukemia (T-PLL) is a rare mature T cell lymphoproliferative disease. It has been associated with an aggressive course, a poor response to conventional chemotherapy and a short median survival. Here we present a rare case of concurrent T-PLL and Kaposi sarcoma who achieved a complete hematologic and cytogenetic remission after a very short course of treatment with alemtuzumab. A review of T-PLL was done. In this review, clinical features, laboratory features and current therapeutic strategies of T-PLL are presented. Copyright (C) 2012 S. Karger AG, Basel
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