Journal
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS
Volume 68, Issue -, Pages 962-964Publisher
INT UNION CRYSTALLOGRAPHY
DOI: 10.1107/S1744309112032435
Keywords
REV1; REV3; REV7; translesion DNA synthesis
Funding
- KAKENHI [18770091, 20770089, 22770109]
- Protein 3000 Project
- Targeted Proteins Research Program (TPRP)
- Grants-in-Aid for Scientific Research [22770109, 18770091, 24657076, 23121524, 20770089] Funding Source: KAKEN
Ask authors/readers for more resources
REV1, REV3 and REV7 are pivotal proteins in translesion DNA synthesis that allows DNA synthesis to continue even in the presence of DNA damage. REV1 and REV3 are error-prone DNA polymerases, while REV7 acts as an adaptor protein that links them together. A ternary complex of the C-terminal domain of human REV1 in complex with REV7 bound to a REV3 fragment has been crystallized. The crystals belonged to space group P3121, with unit-cell parameters a = b = 74.7, c = 124.5 angstrom.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available