4.0 Article

NMR in a crystallography-based high-throughput protein structure-determination environment

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INT UNION CRYSTALLOGRAPHY
DOI: 10.1107/S1744309110030320

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  1. NIH, National Institute of General Medical Sciences, Protein Structure Initiative [U54 GM074898]

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An introduction is provided to three papers which compare corresponding protein crystal and NMR solution structures determined by the Joint Center for Structural Genomics (JCSG). Special mention is made of the JCSG strategy for combined use of the two techniques, and of potential applications of the concept of 'reference crystal structures', which is introduced in the following three papers.

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