(E)-1-(2-Thienyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one

The molecule of the title heteroaryl chalcone, C(16)H(16)O(4)S, which consists of substituted thiophene and benzene rings bridged by the prop-2-en-1-one group, is slightly twisted. The dihedral angle between the thiophene and 3,4,5-trimethoxyphenyl rings is 12.18 (4)degrees. The three methoxy groups have two different conformations; two methoxy groups are coplanar [C-O-C-C torsion angles = -1.38 (12) and 0.47 (12)degrees] whereas the third is (-)-synclinal with the benzene ring. In the crystal structure, adjacent molecules are linked in a face-to-side manner into chains along the c axis by weak C-H center dot center dot center dot O(enone) interactions. These chains are stacked along the b axis by weak C-H center dot center dot center dot O(methoxy) interactions.