Journal
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
Volume 68, Issue -, Pages 1541-1548Publisher
WILEY-BLACKWELL
DOI: 10.1107/S090744491203836X
Keywords
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Funding
- Indian Council of Medical Research
- Department of Biotechnology (DBT)
- University Grants Commission (UGC), Government of India
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The crystal structure of the region spanning residues 95-146 of the rotavirus nonstructural protein NSP4 from the asymptomatic human strain ST3 was determined at a resolution of 2.5 angstrom. Severe diffraction anisotropy, rotational pseudo-symmetry and twinning complicated the refinement of this structure. A systematic explanation confirming the crystal pathologies and describing how the structure was successfully refined is given in this report.
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