Journal
APPETITE
Volume 54, Issue 1, Pages 225-228Publisher
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.appet.2009.12.002
Keywords
Food; Motivational arousal; Prader-Willi syndrome; Genetics; Learning; Craving
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Funding
- Beebe Trust Research Fellow
- Wales Institute of Cognitive Neuroscience
- MRC [G0801418] Funding Source: UKRI
- Medical Research Council [G0801418B, G0801418] Funding Source: researchfish
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This study focused on genetic and behavioural aspects of one important component of the motivation to eat - how appetitive arousal is elicited through the presentation of food-associated Stimuli. Individuals with Prader-Willi syndrome, a genetic disorder associated with hyperphagia, and control participants completed a computerised response task in the presence of motivational stimuli. in controls, appetitive arousal was specific to particular Stimuli. In contrast, individuals with PWS showed a non-specific pattern of arousal. Over-activation of the anticipatory motivation system may be one consequence of the genetic disorder in PWS. (C) 2009 Elsevier Ltd. All rights reserved.
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