Journal
ACTA BIOMATERIALIA
Volume 10, Issue 1, Pages 11-25Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.actbio.2013.08.022
Keywords
Electrospinning; Tubular scaffolds; Vascular grafts; Tissue engineering; Mechanical properties
Funding
- Natural Sciences and Engineering Research Council of Canada (NSERC)
- National Health and Medical Research Council
- Fonds Quebecois de la Recherche sur la Nature et les Technologies (FRQS, Canada)
- National Science Foundation CAREER Award [DMR 0847287]
- office of Naval Research Young National Investigator Award
- National Institutes of Health [HL092836, DE019024, EB012597, AR057837, DE021468, HL099073, EB008392]
- Presidential Early Career Award for Scientists and Engineers (PECASE)
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [R01HL092836, F32HL009907, R01HL099073] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES [R01AR057837] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [R01EB008392, R01EB012597] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH [R01DE021468] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF DENTAL &CRANIOFACIAL RESEARCH [RL1DE019024] Funding Source: NIH RePORTER
Ask authors/readers for more resources
There is a growing demand for off-the-shelf tissue engineered vascular grafts (TEVGs) for the replacement or bypass of damaged arteries in various cardiovascular diseases. Scaffolds from the decellularized tissue skeletons to biopolymers and biodegradable synthetic polymers have been used for fabricating TEVGs. However, several issues have not yet been resolved, which include the inability to mimic the mechanical properties of native tissues, and the ability for long-term patency and growth required for in vivo function. Electrospinning is a popular technique for the production of scaffolds that has the potential to address these issues. However, its application to human TEVGs has not yet been achieved. This review provides an overview of tubular scaffolds that have been prepared by electrospinning with potential for TEVG applications. (C) 2013 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available