Journal
ACTA BIOMATERIALIA
Volume 10, Issue 10, Pages 4023-4042Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.actbio.2014.05.022
Keywords
Biosynthesis; Metallic nanoparticles; Nanomedicine; Bioimaging; Sensors
Funding
- Grant Agency of the Czech Republic [P302/12/G157]
- Charles University in Prague [UNCE 204022, Prvouk/1LF/1]
- European Regional Development Fund [CZ.1.05/1.1.00/02.0109, CZ.2.16/3.1.00/24010]
- [NSF 1242167]
- Directorate For Engineering
- Div Of Engineering Education and Centers [1242167] Funding Source: National Science Foundation
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We present a comprehensive review of the applications of biosynthesized metallic nanoparticles (NPs). The biosynthesis of metallic NPs is the subject of a number of recent reviews, which focus on the various bottom-up biofabrication methods and characterization of the final products. Numerous applications exploit the advantages of biosynthesis over chemical or physical NP syntheses, including lower capital and operating expenses, reduced environmental impacts, and superior biocompatibility and stability of the NP products. The key applications reviewed here include biomedical applications, especially antimicrobial applications, but also imaging applications, catalytic applications such as reduction of environmental contaminants, and electrochemical applications including sensing. The discussion of each application is augmented with a critical review of the potential for continued development. (C) 2014 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
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