Journal
ACTA BIOMATERIALIA
Volume 9, Issue 4, Pages 6150-6157Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.actbio.2012.11.025
Keywords
Nanoparticles; Biosensors; Superparamagnetism; Magnetic properties; Ligand exchange
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Magnetic iron oxide nanoparticles differing in their size, shape (spherical, hexagonal, rods, cubes) and composition have been synthesized and modified using caffeic acid for transfer to aqueous media and stabilization of the particle suspensions at physiological pH. A super quantum interference device and the recently patented magnetic sensor MIAplex (R), which registered a signal proportional to the second derivative of the magnetization curve, were used to study the magnetization behavior of the nanopartides. The differences in the magnetic signatures of the nanoparticles (spheres and rods) make them promising candidates for the simultaneous detection of different types of biological molecules. (C) 2012 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
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