Journal
ACTA BIOMATERIALIA
Volume 7, Issue 2, Pages 478-484Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.actbio.2010.08.008
Keywords
Biomaterial; Bone; Tissue engineering; Resorbable; Graft
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Hundreds of studies have been devoted to the search for the ideal architecture for bone scaffold. Despite these efforts, results are often contradictory, and rules derived from these studies are accordingly vague. In fact, there is enough evidence to postulate that ideal scaffold architecture does not exist. The aim of this document is to explain this statement and review new approaches to decipher the existing but complex link between scaffold architecture and in vivo response. (C) 2010 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
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