Journal
ACTA BIOCHIMICA ET BIOPHYSICA SINICA
Volume 44, Issue 11, Pages 897-901Publisher
OXFORD UNIV PRESS
DOI: 10.1093/abbs/gms067
Keywords
FOXO; phosphorylation; acetylation; ubiquitination; methylation
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Funding
- National Science Foundation of China [81125010, 81030025]
- Ministry of Science and Technology of China [973-2009CB918704, 973-2012CB910701]
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The Forkhead box O (FOXO) family transcription factors play critical roles in a series of cellular processes, including the cell cycle, cell death, metabolism, and oxidative stress resistance. FOXO proteins are subject to several post-translational modifications, which are closely related to their activity. In this paper, we review the post-translational modifications of FOXOs and their biological functions.
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