Journal
ACS NANO
Volume 7, Issue 11, Pages 9753-9760Publisher
AMER CHEMICAL SOC
DOI: 10.1021/nn403241f
Keywords
two-dimensional materials; MoO3; bovine serum albumin; biosensing; exfoliation
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Funding
- Australian Research Council [DP110100262, DP1092717, LE100100215]
- School of Graduate Research at RMIT University
- CSIRO Sensors and Sensor Networks Transformational Capability Platform (SSN TCP)
- CSIRO Materials Science and Engineering Division (CMSE)
- Australian Research Council [LE100100215] Funding Source: Australian Research Council
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Electrical-based biosensing platforms offer ease of fabrication and simple sensing solutions. Recently, two-dimensional (2D) semiconductors have been proven to be excellent for the fabrication of field effect transistors (FETs) due to their large transconductance, which can be efficiently used for developing sensitive bioplatforms. We present a 2D molybdenum trioxide (MoO3) FIT based biosensing platform, using bovine serum albumin as a model protein. The conduction channel is a nanostructured film made of 2D alpha-MoO3 nanoflakes, with the majority of nanoflake thicknesses being equal to or less than 2.8 nm. The response time is impressively low (less than 10 s), which is due to the high permittivity of the 2D alpha-MoO3 nanoflakes. The system offers a competitive solution for future biosensing applications.
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