4.4 Article

The comorbidity of anxiety disorders in bipolar I and bipolar II patients among Turkish population

Journal

JOURNAL OF ANXIETY DISORDERS
Volume 25, Issue 5, Pages 661-667

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.janxdis.2011.02.008

Keywords

Bipolar disorder type I; Bipolar disorder type II; Anxiety disorders; Consequences of comorbidity

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High rates of anxiety disorders have been reported in bipolar disorders. The study aimed to investigate prevalence of anxiety disorders in remitted bipolar subjects and their influence on the illness severity. Bipolar subjects with anxiety disorders were younger, had earlier age at onset of illness, and were over-represented by female subjects and those with earlier onset illness compared to those without anxiety disorder. The study demonstrated that (1) anxiety disorders are highly prevalent in bipolar subjects, (2) individual anxiety disorders, particularly SP and PD seem to have an effect on illness severity, (3) bipolar subjects with comorbid anxiety tend to have a poorer course and are less responsive to treatment, and (4) anxiety tends to be associated with an earlier age at onset of bipolar disorder (BPD) and results in a more complicated and severe disease course. (C) 2011 Elsevier Ltd. All rights reserved.

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