Journal
ACS NANO
Volume 4, Issue 12, Pages 7387-7394Publisher
AMER CHEMICAL SOC
DOI: 10.1021/nn1022582
Keywords
graphene; lipid bilayer; membrane disruption; bioelectronic interface; biomolecular doping; ionic screening
Categories
Funding
- NRF [R-143-000-360- 281]
- Ministry of Education of Singapore [R-143-000-358-112]
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The electronic properties of graphene can be modulated by charged lipid bilayer adsorbing on the surface. Biorecognition events which lead to changes in membrane integrity can be monitored electrically using an electrolyte-gated biomimetic membrane-graphene transistor. Here, we demonstrate that the bactericidal activity of antimicrobial peptides can be sensed electrically by graphene based on a complex interplay of biomolecular doping and ionic screening effect.
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